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Jonathan R. Warner
Department of Cell Biology, Albert Einstein College of Medicine, New York, United States of America

Faculty Member: Cell Biology > Control of Gene Expression [ since 25 July 2001 ]
[ Biography ] [ Evaluations ]
Biography

PhD MIT ''63
Faculty, Albert Einstein College of Medicine, ''65-present
Formerly, Director Graduate School, ''73-''83
Formerly, Chair Cell Biology Dep''t ''83-''98
Currently, Prof. Cell Biology

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Evaluations

Visual analysis of the yeast 5S rRNA gene transcriptome: regulation and role of La protein.
French SL, Osheim YN, …, Wolin SL, Beyer AL
Mol Cell Biol 2008 Jul 28(14):4576-87 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 1 Jul 2008

MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation.
Ørom UA, Nielsen FC, Lund AH
Mol Cell 2008 May 23 30(4):460-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner / Paul Lasko / Peter Sarnow
Evaluated 4 Jun 2008

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
West S, Proudfoot NJ, Dye MJ
Mol Cell 2008 Mar 14 29(5):600-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 31 Mar 2008

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.
Ebert BL, Pretz J, …, Ellis SR, Golub TR
Nature 2008 Jan 17 451(7176):335-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew Wilkie / Jonathan R. Warner / Scott Lowe
Evaluated 29 Jan 2008


Analysis of the in vivo assembly pathway of eukaryotic 40S ribosomal proteins.
Ferreira-Cerca S, Pöll G, …, Tschochner H, Milkereit P
Mol Cell 2007 Nov 9 28(3):446-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 26 Nov 2007

What is a gene, post-ENCODE? History and updated definition.
Gerstein MB, Bruce C, …, Weissman S, Snyder M
Genome Res 2007 Jun 17(6):669-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 24 Aug 2007

Inhibition of c-Myc activity by ribosomal protein L11.
Dai MS, Arnold H, …, Sears R, Lu H
EMBO J 2007 Jul 25 26(14):3332-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laura Johnston / Jonathan R. Warner
Evaluated 17 Aug 2007

A chromatin landmark and transcription initiation at most promoters in human cells.
Guenther MG, Levine SS, …, Jaenisch R, Young RA
Cell 2007 Jul 13 130(1):77-88 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner / Michael Cole
Evaluated 27 Jul 2007

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.
Roux PP, Shahbazian D, …, Sonenberg N, Blenis J
J Biol Chem 2007 May 11 282(19):14056-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 25 May 2007

Transcriptional noise and the fidelity of initiation by RNA polymerase II.
Struhl K
Nat Struct Mol Biol 2007 Feb 14(2):103-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 9 Feb 2007

A large-scale full-length cDNA analysis to explore the budding yeast transcriptome.
Miura F, Kawaguchi N, …, Morishita S, Ito T
Proc Natl Acad Sci U S A 2006 Nov 21 103(47):17846-51 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 5 Dec 2006

Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation.
Panić L, Tamarut S, …, Grabusić K, Volarević S
Mol Cell Biol 2006 Dec 26(23):8880-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 16 Oct 2006

Expression of rRNA genes and nucleolus formation at ectopic chromosomal sites in the yeast Saccharomyces cerevisiae.
Oakes ML, Johzuka K, …, Eliason K, Nomura M
Mol Cell Biol 2006 Aug 26(16):6223-38 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 18 Aug 2006

The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components.
Laferté A, Favry E, …, Carles C, Chédin S
Genes Dev 2006 Aug 1 20(15):2030-40 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Jurg Bahler
Evaluated 18 Aug 2006

Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit.
Schäfer T, Maco B, …, Aebi U, Hurt E
Nature 2006 Jun 1 441(7093):651-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner / Arlen Johnson
Evaluated 13 Jun 2006

Mammalian sperm translate nuclear-encoded proteins by mitochondrial-type ribosomes.
Gur Y, Breitbart H
Genes Dev 2006 Feb 15 20(4):411-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 20 Feb 2006

Human ribosomal RNA gene arrays display a broad range of palindromic structures.
Caburet S, Conti C, …, Edelstein SJ, Bensimon A
Genome Res 2005 Aug 15(8):1079-85 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 26 Jan 2006

A protein component at the heart of an RNA machine: the importance of protein l27 for the function of the bacterial ribosome.
Maguire BA, Beniaminov AD, …, Mankin AS, Zimmermann RA
Mol Cell 2005 Nov 11 20(3):427-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 18 Nov 2005

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.
Ruvinsky I, Sharon N, …, Zisman P, Meyuhas O
Genes Dev 2005 Sep 15 19(18):2199-211 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 26 Sep 2005

Targets of microRNA regulation in the Drosophila oocyte proteome.
Nakahara K, Kim K, …, Minden JS, Carthew RW
Proc Natl Acad Sci U S A 2005 Aug 23 102(34):12023-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 25 Aug 2005

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.
Korgaonkar C, Hagen J, …, Quelle FW, Quelle DE
Mol Cell Biol 2005 Feb 25(4):1258-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 25 Aug 2005

Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Yuan X, Zhou Y, …, Schütz G, Grummt I
Mol Cell 2005 Jul 1 19(1):77-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sui Huang / Jonathan R. Warner
Evaluated 25 Jul 2005

Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation.
Menon BB, Sarma NJ, …, Andrews B, Santangelo GM
Proc Natl Acad Sci U S A 2005 Apr 19 102(16):5749-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Rivka Dikstein
Evaluated 19 Apr 2005

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I.
Grandori C, Gomez-Roman N, …, Eisenman RN, White RJ
Nat Cell Biol 2005 Mar 7(3):311-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner / Lucio Comai
Evaluated 15 Mar 2005

A genetic and molecular characterization of two proximal heterochromatic genes on chromosome 3 of Drosophila melanogaster.
Schulze SR, Sinclair DA, Fitzpatrick KA, Honda BM
Genetics 2005 Apr 169(4):2165-77 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 2 Mar 2005

Global nucleosome occupancy in yeast.
Bernstein BE, Liu CL, …, Perlstein EO, Schreiber SL
Genome Biol 2004 5(9):R62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 11 Nov 2004

Mapping global histone acetylation patterns to gene expression.
Kurdistani SK, Tavazoie S, Grunstein M
Cell 2004 Jun 11 117(6):721-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hiten Madhani / Michael Meisterernst / Jonathan R. Warner
Evaluated 14 Jul 2004

Targeted mRNA degradation by deadenylation-independent decapping.
Badis G, Saveanu C, Fromont-Racine M, Jacquier A
Mol Cell 2004 Jul 2 15(1):5-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 13 Jul 2004

MrpL36p, a highly diverged L31 ribosomal protein homolog with additional functional domains in Saccharomyces cerevisiae mitochondria.
Williams EH, Perez-Martinez X, Fox TD
Genetics 2004 May 167(1):65-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 7 Jun 2004

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.
Pende M, Um SH, …, Kozma SC, Thomas G
Mol Cell Biol 2004 Apr 24(8):3112-24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 8 Apr 2004

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses.
Rubbi CP, Milner J
EMBO J 2003 Nov 17 22(22):6068-77 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Lucio Comai / Christoph Borner
Evaluated 12 Jan 2004

Global analysis of protein expression in yeast.
Ghaemmaghami S, Huh WK, …, O'Shea EK, Weissman JS
Nature 2003 Oct 16 425(6959):737-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means / John Yates / Anita Hopper / Anne Osbourn / Suresh Subramani / Sally Zigmond
Dissenters | Jonathan R. Warner
Author Response | Jonathan Weissman
Evaluated 19 Nov 2003


Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control.
Mazumder B, Sampath P, …, DiCorleto PE, Fox PL
Cell 2003 Oct 17 115(2):187-98 [abstract on PubMed] [related articles] [order article]
Selected by | Christopher Nicchitta / Jonathan R. Warner / Elizabeth Gavis / Miles Wilkinson
Evaluated 28 Oct 2003

Control of rRNA expression by small molecules is dynamic and nonredundant.
Murray HD, Schneider DA, Gourse RL
Mol Cell 2003 Jul 12(1):125-34 [abstract on PubMed] [related articles] [order article]
Selected by | Thomas Nystrom / Jonathan R. Warner
Evaluated 30 Sep 2003

Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between RNA polymerase I and II.
Cioci F, Vu L, …, Siddiqi IN, Nomura M
Mol Cell 2003 Jul 12(1):135-45 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathan R. Warner
Evaluated 30 Sep 2003

Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae.
Arava Y, Wang Y, …, Brown PO, Herschlag D
Proc Natl Acad Sci U S A 2003 Apr 1 100(7):3889-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Jon Lorsch
Evaluated 7 Apr 2003

In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes.
French SL, Osheim YN, …, Nomura M, Beyer AL
Mol Cell Biol 2003 Mar 23(5):1558-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Lucio Comai
Evaluated 28 Feb 2003

Nuclear translation: what is the evidence?
Dahlberg JE, Lund E, Goodwin EB
RNA 2003 Jan 9(1):1-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anita Hopper / Jonathan R. Warner
Evaluated 11 Feb 2003

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification.
Ruggero D, Grisendi S, …, Cordon-Cardo C, Pandolfi PP
Science 2003 Jan 10 299(5604):259-62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Roy Long
Evaluated 17 Jan 2003

The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila.
Andrulis ED, Werner J, …, Tempst P, Lis JT
Nature 2002 Dec 19-26 420(6917):837-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arlen Johnson / Carl Thummel / Jonathan R. Warner / David Tollervey
Evaluated 17 Jan 2003

Transcriptional regulatory networks in Saccharomyces cerevisiae.
Lee TI, Rinaldi NJ, …, Gifford DK, Young RA
Science 2002 Oct 25 298(5594):799-804 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Rob White / Jonathan R. Warner / Yasushi Okazaki / Regine Hengge / Oliver Fiehn / Philip Benfey / Roger Brent
Evaluated 12 Nov 2002

One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.
Inada T, Winstall E, …, Schieltz D, Sachs AB
RNA 2002 Jul 8(7):948-58 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 3 Sep 2002

Ribosome components are associated with sites of transcription.
Brogna S, Sato TA, Rosbash M
Mol Cell 2002 Jul 10(1):93-104 [abstract on PubMed] [related articles] [order article]
Selected by | Lynne Maquat / David Tollervey / Carl Thummel / Peter B. Becker / Miles Wilkinson / Jonathan R. Warner / Elsebet Lund
Evaluated 3 Sep 2002

Translational machinery of channel catfish: I. A transcriptomic approach to the analysis of 32 40S ribosomal protein genes and their expression.
Karsi A, Patterson A, Feng J, Liu Z
Gene 2002 May 29 291(1-2):177-86 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathan R. Warner
Evaluated 17 Jul 2002

NTP-sensing by rRNA promoters in Escherichia coli is direct.
Schneider DA, Gaal T, Gourse RL
Proc Natl Acad Sci U S A 2002 Jun 25 99(13):8602-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 27 Jun 2002

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
Jurica MS, Licklider LJ, …, Grigorieff N, Moore MJ
RNA 2002 Apr 8(4):426-39 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 13 May 2002

Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast.
Mencía M, Moqtaderi Z, …, Kuras L, Struhl K
Mol Cell 2002 Apr 9(4):823-33 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathan R. Warner
Evaluated 9 May 2002

Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays.
Clark TA, Sugnet CW, Ares M
Science 2002 May 3 296(5569):907-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner / Anita Hopper
Evaluated 9 May 2002

Composition and functional characterization of the yeast spliceosomal penta-snRNP.
Stevens SW, Ryan DE, …, Lee TD, Abelson J
Mol Cell 2002 Jan 9(1):31-44 [abstract on PubMed] [related articles] [order article]
Selected by | Jon Lorsch / Jonathan R. Warner / Adrian Krainer
Evaluated 20 Feb 2002

Differential effects of replacing Escherichia coli ribosomal protein L27 with its homologue from Aquifex aeolicus.
Maguire BA, Manuilov AV, Zimmermann RA
J Bacteriol 2001 Nov 183(22):6565-72 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan R. Warner
Evaluated 3 Dec 2001

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