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Richard Gourse
Department of Bacteriology, University of Wisconsin-Madison, Madison, United States of America

Faculty Member: Microbiology > Microbial Physiology & Metabolism [ since 6 July 2001 ]
[ Sponsorship ] [ Homepage ] [ Evaluations ]
Sponsorship

Richard Gourse sponsors free access to F1000 for Centro de Investigación sobre Fijación de Nitrógeno - Universidad Nacional Autónoma de México (CIFN-UNAM), Morelos, Mexico. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details).

Home page

http://www.bact.wisc.edu/GradStudies/GourseRichard.htm

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Evaluations

Identification and functional analysis of novel (p)ppGpp synthetase genes in Bacillus subtilis.
Nanamiya H, Kasai K, …, Kawamura F, Tozawa Y
Mol Microbiol 2008 Jan 67(2):291-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 25 Jan 2008

The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal.
Deana A, Celesnik H, Belasco JG
Nature 2008 Jan 17 451(7176):355-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse / Stephen Busby
Evaluated 21 Jan 2008

Performance of the translational apparatus varies with the ecological strategies of bacteria.
Dethlefsen L, Schmidt TM
J Bacteriol 2007 Apr 189(8):3237-45 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 25 Apr 2007

Nutritional control of elongation of DNA replication by (p)ppGpp.
Wang JD, Sanders GM, Grossman AD
Cell 2007 Mar 9 128(5):865-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 9 Mar 2007

RNA-mediated destabilization of the sigma(70) region 4/beta flap interaction facilitates engagement of RNA polymerase by the Q antiterminator.
Nickels BE, Roberts CW, Roberts JW, Hochschild A
Mol Cell 2006 Nov 3 24(3):457-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 8 Jan 2007

ppGpp with DksA controls gene expression in the locus of enterocyte effacement (LEE) pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes.
Nakanishi N, Abe H, …, Sugimoto N, Tobe T
Mol Microbiol 2006 Jul 61(1):194-205 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 17 Jul 2006

Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli.
Bougdour A, Wickner S, Gottesman S
Genes Dev 2006 Apr 1 20(7):884-97 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 21 Apr 2006

The structural basis of cooperative regulation at an alternate genetic switch.
Pinkett HW, Shearwin KE, …, Egan JB, Lewis M
Mol Cell 2006 Mar 3 21(5):605-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 16 Mar 2006

Structural basis for bacterial transcription-coupled DNA repair.
Deaconescu AM, Chambers AL, …, Savery NJ, Darst SA
Cell 2006 Feb 10 124(3):507-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 16 Feb 2006

Holoenzyme switching and stochastic release of sigma factors from RNA polymerase in vivo.
Raffaelle M, Kanin EI, …, Burgess RR, Ansari AZ
Mol Cell 2005 Nov 11 20(3):357-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 14 Nov 2005

A transcriptional response to singlet oxygen, a toxic byproduct of photosynthesis.
Anthony JR, Warczak KL, Donohue TJ
Proc Natl Acad Sci U S A 2005 May 3 102(18):6502-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Spiro / Richard Gourse
Evaluated 17 May 2005

The interaction between sigma70 and the beta-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation.
Nickels BE, Garrity SJ, …, Ebright RH, Hochschild A
Proc Natl Acad Sci U S A 2005 Mar 22 102(12):4488-93 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse / Regine Hengge
Evaluated 21 Mar 2005

mRNA helicase activity of the ribosome.
Takyar S, Hickerson RP, Noller HF
Cell 2005 Jan 14 120(1):49-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kathleen Hall / Gloria Culver / Richard Gourse / Reinhard Luehrmann
Evaluated 18 Feb 2005

The Escherichia coli GTPase CgtAE cofractionates with the 50S ribosomal subunit and interacts with SpoT, a ppGpp synthetase/hydrolase.
Wout P, Pu K, …, Lin B, Maddock JR
J Bacteriol 2004 Aug 186(16):5249-57 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 7 Oct 2004

Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25.
Adelman K, Yuzenkova J, …, Wang MD, Severinov K
Mol Cell 2004 Jun 18 14(6):753-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 2 Jul 2004

Antibacterial peptide microcin J25 inhibits transcription by binding within and obstructing the RNA polymerase secondary channel.
Mukhopadhyay J, Sineva E, …, Levy RM, Ebright RH
Mol Cell 2004 Jun 18 14(6):739-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse
Evaluated 2 Jul 2004

Osmo-regulation of bacterial transcription via poised RNA polymerase.
Lee SJ, Gralla JD
Mol Cell 2004 Apr 23 14(2):153-62 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 27 Apr 2004

Structure of a ternary transcription activation complex.
Jain D, Nickels BE, …, Hochschild A, Darst SA
Mol Cell 2004 Jan 16 13(1):45-53 [abstract on PubMed] [related articles] [order article]
Selected by | Hiroji Aiba / Richard Gourse
Evaluated 10 Feb 2004

Cleavage of the A site mRNA codon during ribosome pausing provides a mechanism for translational quality control.
Hayes CS, Sauer RT
Mol Cell 2003 Oct 12(4):903-11 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 11 Nov 2003

Phage N4 RNA polymerase II recruitment to DNA by a single-stranded DNA-binding protein.
Carter RH, Demidenko AA, Hattingh-Willis S, Rothman-Denes LB
Genes Dev 2003 Sep 15 17(18):2334-45 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 18 Sep 2003

Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA.
Campbell EA, Tupy JL, …, Gross CA, Darst SA
Mol Cell 2003 Apr 11(4):1067-78 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 18 Sep 2003

Functional interaction between RNA polymerase alpha subunit C-terminal domain and sigma70 in UP-element- and activator-dependent transcription.
Chen H, Tang H, Ebright RH
Mol Cell 2003 Jun 11(6):1621-33 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 9 Jul 2003

Transcription termination control of the S box system: direct measurement of S-adenosylmethionine by the leader RNA.
McDaniel BA, Grundy FJ, Artsimovitch I, Henkin TM
Proc Natl Acad Sci U S A 2003 Mar 18 100(6):3083-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 12 Mar 2003

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.
Winkler W, Nahvi A, Breaker RR
Nature 2002 Oct 31 419(6910):952-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Burke / Richard Maraia / Richard Gourse / Andrew Ellington / Niles Lehman / Gabriele Varani
Evaluated 19 Nov 2002

Protein-protein and protein-DNA interactions of sigma70 region 4 involved in transcription activation by lambdacI.
Nickels BE, Dove SL, …, Darst SA, Hochschild A
J Mol Biol 2002 Nov 15 324(1):17-34 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 19 Nov 2002

Instruction of translating ribosome by nascent peptide.
Gong F, Yanofsky C
Science 2002 Sep 13 297(5588):1864-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse / Jorge C. Escalante-Semerena
Evaluated 30 Sep 2002

Structural basis of transcription activation: the CAP-alpha CTD-DNA complex.
Benoff B, Yang H, …, Berman HM, Ebright RH
Science 2002 Aug 30 297(5586):1562-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby / Peter Qin / Richard Gourse
Evaluated 13 Sep 2002

The DnaK chaperone system facilitates 30S ribosomal subunit assembly.
Maki JA, Schnobrich DJ, Culver GM
Mol Cell 2002 Jul 10(1):129-38 [abstract on PubMed] [related articles] [order article]
Selected by | Sarah Woodson / Richard Gourse
Evaluated 6 Sep 2002

E. coli Transcription repair coupling factor (Mfd protein) rescues arrested complexes by promoting forward translocation.
Park JS, Marr MT, Roberts JW
Cell 2002 Jun 14 109(6):757-67 [abstract on PubMed] [related articles] [order article]
Selected by | Daniel Reines / Richard Gourse
Evaluated 30 Jul 2002

Identification of the tRNA-dihydrouridine synthase family.
Bishop AC, Xu J, …, Schimmel P, de Crécy-Lagard V
J Biol Chem 2002 Jul 12 277(28):25090-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 19 Jul 2002

Regulation of sigma factor competition by the alarmone ppGpp.
Jishage M, Kvint K, Shingler V, Nyström T
Genes Dev 2002 May 15 16(10):1260-70 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse / Regine Hengge
Evaluated 12 Jun 2002

Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Campbell EA, Muzzin O, …, Trester-Zedlitz ML, Darst SA
Mol Cell 2002 Mar 9(3):527-39 [abstract on PubMed] [related articles] [order article]
Selected by | Richard Gourse
Evaluated 3 May 2002

Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length.
Kuznedelov K, Korzheva N, Mustaev A, Severinov K
EMBO J 2002 Mar 15 21(6):1369-78 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse / Donal S. Luse
Evaluated 22 Mar 2002

Inhibition of the B. subtilis regulatory protein TRAP by the TRAP-inhibitory protein, AT.
Valbuzzi A, Yanofsky C
Science 2001 Sep 14 293(5537):2057-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mitzi Kuroda / Richard Gourse
Evaluated 6 Feb 2002

RapA, a bacterial homolog of SWI2/SNF2, stimulates RNA polymerase recycling in transcription.
Sukhodolets MV, Cabrera JE, Zhi H, Jin DJ
Genes Dev 2001 Dec 15 15(24):3330-41 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Gourse
Evaluated 23 Jan 2002

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