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Lawrence A Chasin
Department of Biological Sciences, Columbia University, New York, United States of America

Faculty Member: CELL BIOLOGY > Control of gene expression [ since 14 June 2002 ]
[ Homepage ] [ Evaluations ]
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http://www.columbia.edu/cu/biology/faculty/chasin/index.html

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Evaluations

Oriented scanning is the leading mechanism underlying 5' splice site selection in mammals.
Borensztajn K, Sobrier ML, …, Tapon-Bretaudière J, Amselem S
PLoS Genet 2006 Sep 1 2(9):e138 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 28 May 2008

Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum.
Pyhtila B, Zheng T, …, Reedy MC, Nicchitta CV
RNA 2008 Mar 14(3):445-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin / Davis Ng
Evaluated 26 Feb 2008

The genetic code is nearly optimal for allowing additional information within protein-coding sequences.
Itzkovitz S, Alon U
Genome Res 2007 Apr 17(4):405-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin / Panayiotis (Takis) Benos
Evaluated 13 Apr 2007

Inference of splicing regulatory activities by sequence neighborhood analysis.
Stadler MB, Shomron N, …, Xiao X, Burge CB
PLoS Genet 2006 Nov 24 2(11):e191 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 24 Jan 2007

RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.
Shen H, Green MR
Genes Dev 2006 Jul 1 20(13):1755-65 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 28 Jul 2006

Exon tethering in transcription by RNA polymerase II.
Dye MJ, Gromak N, Proudfoot NJ
Mol Cell 2006 Mar 17 21(6):849-59 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin / Benoit Coulombe / Miles Wilkinson
Evaluated 23 Mar 2006

Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing.
Martinez-Contreras R, Fisette JF, …, Cordeau M, Chabot B
PLoS Biol 2006 Feb 4(2):e21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 17 Jan 2006

The relationship among gene expression, folding free energy and codon usage bias in Escherichia coli.
Jia M, Li Y
FEBS Lett 2005 Oct 10 579(24):5333-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin
Evaluated 7 Dec 2005

Distribution of SR protein exonic splicing enhancer motifs in human protein-coding genes.
Wang J, Smith PJ, Krainer AR, Zhang MQ
Nucleic Acids Res 2005 33(16):5053-62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 6 Oct 2005

Structure of PTB bound to RNA: specific binding and implications for splicing regulation.
Oberstrass FC, Auweter SD, …, Black DL, Allain FH
Science 2005 Sep 23 309(5743):2054-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin / Reinhard Luehrmann
Evaluated 4 Oct 2005

Kinetics and thermodynamics make different contributions to RNA folding in vitro and in yeast.
Mahen EM, Harger JW, Calderon EM, Fedor MJ
Mol Cell 2005 Jul 1 19(1):27-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin
Evaluated 18 Jul 2005

DIP-chip: rapid and accurate determination of DNA-binding specificity.
Liu X, Noll DM, Lieb JD, Clarke ND
Genome Res 2005 Mar 15(3):421-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 22 Apr 2005

Small molecule control of pre-mRNA splicing.
Graveley BR
RNA 2005 Mar 11(3):355-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 16 Feb 2005

Commitment to splice site pairing coincides with A complex formation.
Lim SR, Hertel KJ
Mol Cell 2004 Aug 13 15(3):477-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin
Evaluated 12 Oct 2004

Nutritional homeostasis in batch and steady-state culture of yeast.
Saldanha AJ, Brauer MJ, Botstein D
Mol Biol Cell 2004 Sep 15(9):4089-104 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin / Daniel Dykhuizen
Evaluated 29 Sep 2004

A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2.
Shen H, Kan JL, …, Biamonti G, Green MR
RNA 2004 May 10(5):787-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 22 Apr 2004

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex.
Chiu SY, Lejeune F, Ranganathan AC, Maquat LE
Genes Dev 2004 Apr 1 18(7):745-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin / Miles Wilkinson
Evaluated 14 Apr 2004

Analysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry.
Rhode BM, Hartmuth K, Urlaub H, Luhrmann R
RNA 2003 Dec 9(12):1542-51 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 26 Feb 2004

Patterns of nucleotide substitution, insertion and deletion in the human genome inferred from pseudogenes.
Zhang Z, Gerstein M
Nucleic Acids Res 2003 Sep 15 31(18):5338-48 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 16 Sep 2003

Alu-containing exons are alternatively spliced.
Sorek R, Ast G, Graur D
Genome Res 2002 Jul 12(7):1060-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin
Evaluated 4 Jun 2003

Pentamer vocabularies characterizing introns and intron-like intergenic tracts from Caenorhabditis elegans and Drosophila melanogaster.
Bultrini E, Pizzi E, Del Giudice P, Frontali C
Gene 2003 Jan 30 304:183-92 [abstract on PubMed] [related articles] [order article]
Selected by | Lawrence Chasin
Evaluated 27 Feb 2003

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly.
Reichert VL, Le Hir H, Jurica MS, Moore MJ
Genes Dev 2002 Nov 1 16(21):2778-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson / Lawrence Chasin
Evaluated 27 Feb 2003

Predictive identification of exonic splicing enhancers in human genes.
Fairbrother WG, Yeh RF, Sharp PA, Burge CB
Science 2002 Aug 9 297(5583):1007-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David States / Lawrence Chasin / Gabriele Varani
Evaluated 29 Jul 2002

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