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Jane Endicott
University of Oxford, United Kingdom

Faculty Member: CELL BIOLOGY > Cell growth & division [ since 12 April 2002 ]
[ On Sabbatical from 04-MAR-2008 to 31-AUG-2008 ]
[ Evaluations ]
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Evaluations

E1-L2 activates both ubiquitin and FAT10.
Chiu YH, Sun Q, Chen ZJ
Mol Cell 2007 Sep 21 27(6):1014-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 30 Oct 2007

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
Christensen DE, Brzovic PS, Klevit RE
Nat Struct Mol Biol 2007 Oct 14(10):941-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brian Kuhlman / Jane Endicott / Thomas Kodadek
Evaluated 25 Oct 2007

20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals.
Le Tallec B, Barrault MB, …, Marsolier-Kergoat MC, Peyroche A
Mol Cell 2007 Aug 17 27(4):660-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 14 Sep 2007

Autocatalytic phosphorylation of CDK2 at the activating Thr160.
Abbas T, Jha S, Sherman NE, Dutta A
Cell Cycle 2007 Apr 6(7):843-52 [abstract on PubMed] [related articles] [order article]
Selected by | Jane Endicott
Evaluated 25 Apr 2007

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Stegmeier F, Rape M, …, Harper JW, Elledge SJ
Nature 2007 Apr 19 446(7138):876-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Kyriakis / Jane Endicott
Evaluated 25 Apr 2007

The site-specific installation of methyl-lysine analogs into recombinant histones.
Simon MD, Chu F, …, Narlikar GJ, Shokat KM
Cell 2007 Mar 9 128(5):1003-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Song Tan / Jane Endicott
Evaluated 25 Apr 2007

Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis.
Kanin EI, Kipp RT, …, Shokat KM, Ansari AZ
Proc Natl Acad Sci U S A 2007 Apr 3 104(14):5812-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Thomas Kodadek / Jane Endicott
Evaluated 25 Apr 2007

Structure and regulation of the human Nek2 centrosomal kinase.
Rellos P, Ivins FJ, …, Knapp S, Smerdon SJ
J Biol Chem 2007 Mar 2 282(9):6833-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 9 Feb 2007

Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Huang DT, Hunt HW, …, Holton JM, Schulman BA
Nature 2007 Jan 25 445(7126):394-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zhen-Qiang Pan / Jane Endicott / Frank Sicheri
Evaluated 9 Feb 2007

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
Binné UK, Classon MK, …, Näär AM, Dyson NJ
Nat Cell Biol 2007 Feb 9(2):225-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 9 Feb 2007

Yeast Pth2 is a UBL domain-binding protein that participates in the ubiquitin-proteasome pathway.
Ishii T, Funakoshi M, Kobayashi H
EMBO J 2006 Nov 29 25(23):5492-503 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 28 Nov 2006

Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.
Gutierrez GJ, Vögtlin A, …, Lorca T, Nebreda AR
Nat Cell Biol 2006 Oct 8(10):1084-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 28 Nov 2006

A ubiquitin ligase complex assembles linear polyubiquitin chains.
Kirisako T, Kamei K, …, Tanaka K, Iwai K
EMBO J 2006 Oct 18 25(20):4877-87 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 23 Nov 2006

Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Alam SL, Langelier C, …, Hill CP, Sundquist WI
Nat Struct Mol Biol 2006 Nov 13(11):1029-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 23 Nov 2006

Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1.
Ji P, Goldin L, …, Pagano M, Zhu L
J Biol Chem 2006 Aug 18 281(33):24058-69 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 4 Sep 2006

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Zhang X, Gureasko J, …, Cole PA, Kuriyan J
Cell 2006 Jun 16 125(6):1137-49 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Superti-Furga / Stevan Hubbard / Xiayang Qiu / Gourisankar Ghosh / Karen Anderson / Elizabeth Goldsmith / Friedemann Kiefer / Jane Endicott / Frank Sicheri
Evaluated 31 Aug 2006

Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.
Lee S, Tsai YC, …, Bonifacino JS, Hurley JH
Nat Struct Mol Biol 2006 Mar 13(3):264-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 11 Apr 2006

Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting.
Hirano S, Kawasaki M, …, Stenmark H, Wakatsuki S
Nat Struct Mol Biol 2006 Mar 13(3):272-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 11 Apr 2006

The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin.
Reyes-Turcu FE, Horton JR, …, Cheng X, Wilkinson KD
Cell 2006 Mar 24 124(6):1197-208 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 11 Apr 2006

Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34.
Petroski MD, Deshaies RJ
Cell 2005 Dec 16 123(6):1107-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 12 Jan 2006

Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis.
Wang M, Pickart CM
EMBO J 2005 Dec 21 24(24):4324-33 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 12 Jan 2006

Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase.
Li S, Depetris RS, …, Chernoff J, Hubbard SR
Structure 2005 Nov 13(11):1643-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 12 Jan 2006

CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis.
Mailand N, Diffley JF
Cell 2005 Sep 23 122(6):915-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Kearsey / Jane Endicott
Evaluated 5 Oct 2005

Cdc2-cyclin E complexes regulate the G1/S phase transition.
Aleem E, Kiyokawa H, Kaldis P
Nat Cell Biol 2005 Aug 7(8):831-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martine Roussel / Michele Pagano / Jane Endicott
Evaluated 5 Oct 2005

Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase.
Cadwell K, Coscoy L
Science 2005 Jul 1 309(5731):127-30 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karin Romisch / Jane Endicott
Evaluated 23 Aug 2005

A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint.
Rohaly G, Chemnitz J, …, Deppert W, Dornreiter I
Cell 2005 Jul 15 122(1):21-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Jane Endicott
Evaluated 23 Aug 2005

Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain.
Varadan R, Assfalg M, …, Pickart C, Fushman D
Mol Cell 2005 Jun 10 18(6):687-98 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 27 Jun 2005

A small molecule-kinase interaction map for clinical kinase inhibitors.
Fabian MA, Biggs WH, …, Zarrinkar PP, Lockhart DJ
Nat Biotechnol 2005 Mar 23(3):329-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Chernoff / Channing Der / Christopher Thanos / Wolfgang Jahnke / Marilyn Parsons / Jane Endicott
Evaluated 19 May 2005

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.
Gumireddy K, Reddy MV, …, Holland J, Reddy EP
Cancer Cell 2005 Mar 7(3):275-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 6 Apr 2005

The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4-hydroxylases.
van der Wel H, Ercan A, West CM
J Biol Chem 2005 Apr 15 280(15):14645-55 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott / Christopher Schofield
Evaluated 6 Apr 2005

Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein.
Cabantous S, Terwilliger TC, Waldo GS
Nat Biotechnol 2005 Jan 23(1):102-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kees Jalink / Jan Kok / Jane Endicott / Ross Weatherman
Evaluated 8 Feb 2005

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.
Manke IA, Nguyen A, …, Elia AE, Yaffe MB
Mol Cell 2005 Jan 7 17(1):37-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Angel Nebreda / Jane Endicott
Evaluated 8 Feb 2005

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks.
Singleton MR, Dillingham MS, …, Kowalczykowski SC, Wigley DB
Nature 2004 Nov 11 432(7014):187-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barry Stoddard / Jane Endicott / Malcolm White / Anne-Catherine Dock-Bregeon
Evaluated 29 Nov 2004

Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control.
Mimura S, Seki T, Tanaka S, Diffley JF
Nature 2004 Oct 28 431(7012):1118-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott / Gennaro D'Urso / Jonathon Pines
Evaluated 24 Nov 2004

Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly.
Merkley N, Shaw GS
J Biol Chem 2004 Nov 5 279(45):47139-47 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott / Zhen-Qiang Pan
Evaluated 20 Sep 2004

Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A.
Raasi S, Orlov I, Fleming KG, Pickart CM
J Mol Biol 2004 Aug 27 341(5):1367-79 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 20 Sep 2004

Caged phosphopeptides reveal a temporal role for 14-3-3 in G1 arrest and S-phase checkpoint function.
Nguyen A, Rothman DM, …, Imperiali B, Yaffe MB
Nat Biotechnol 2004 Aug 22(8):993-1000 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Jackson / Jane Endicott
Evaluated 13 Sep 2004

Two-substrate association with the 20S proteasome at single-molecule level.
Hutschenreiter S, Tinazli A, Model K, Tampé R
EMBO J 2004 Jul 7 23(13):2488-97 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karin Romisch / Jane Endicott / Sebastian Springer
Evaluated 27 Jul 2004

Skp2-mediated degradation of p27 regulates progression into mitosis.
Nakayama K, Nagahama H, …, Natsume T, Nakayama KI
Dev Cell 2004 May 6(5):661-72 [abstract on PubMed] [related articles] [order article]
Selected by | Michele Pagano / Jane Endicott
Evaluated 29 Jun 2004

Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.
Lehmann A, Katayama S, …, McDonald N, Toda T
Genes Cells 2004 May 9(5):367-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 22 Jun 2004

p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding.
Lacy ER, Filippov I, …, Hengst L, Kriwacki RW
Nat Struct Mol Biol 2004 Apr 11(4):358-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott
Evaluated 18 Jun 2004

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling.
Varadan R, Assfalg M, …, Pickart C, Fushman D
J Biol Chem 2004 Feb 20 279(8):7055-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 19 Mar 2004

The development of a CDK2-docking site peptide that inhibits p53 and sensitizes cells to death.
Ferguson M, Luciani MG, …, Fersht A, Hupp TR
Cell Cycle 2004 Jan 3(1):80-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 17 Mar 2004

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.
Vassilev LT, Vu BT, …, Fotouhi N, Liu EA
Science 2004 Feb 6 303(5659):844-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ulf Pettersson / Liang Tong / Martine Roussel / Jane Endicott / William Kaelin / Dorothee Kern
Evaluated 17 Mar 2004

Control mechanism of the circadian clock for timing of cell division in vivo.
Matsuo T, Yamaguchi S, …, Shimoda F, Okamura H
Science 2003 Oct 10 302(5643):255-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paolo Sassone-Corsi / Jane Endicott
Evaluated 30 Oct 2003

Self-assembly of proteins into designed networks.
Ringler P, Schulz GE
Science 2003 Oct 3 302(5642):106-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven Zimmerman / Jane Endicott
Evaluated 30 Oct 2003

DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a.
Walters KJ, Lech PJ, …, Wang Q, Howley PM
Proc Natl Acad Sci U S A 2003 Oct 28 100(22):12694-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott
Evaluated 30 Oct 2003

Crystal structure of human cytochrome P450 2C9 with bound warfarin.
Williams PA, Cosme J, …, Matak Vinkovi¿ D, Jhoti H
Nature 2003 Jul 24 424(6947):464-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patricia C. Weber / Jane Endicott
Evaluated 6 Aug 2003

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate.
Salmeen A, Andersen JN, …, Tonks NK, Barford D
Nature 2003 Jun 12 423(6941):769-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zhong-Yin Zhang / Jane Endicott / Padmanabhan Balaram
Evaluated 7 Jul 2003

Mechanism of ubiquitin recognition by the CUE domain of Vps9p.
Prag G, Misra S, …, Horazdovsky BF, Hurley JH
Cell 2003 May 30 113(5):609-20 [abstract on PubMed] [related articles] [order article]
Selected by | David Lambright / Jane Endicott
Evaluated 7 Jul 2003

Proliferation of cancer cells despite CDK2 inhibition.
Tetsu O, McCormick F
Cancer Cell 2003 Mar 3(3):233-45 [abstract on PubMed] [related articles] [order article]
Selected by | Jane Endicott / Laura Itzhaki
Evaluated 2 Jun 2003

Rad23 UBA domains inhibit 26S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains.
Raasi S, Pickart CM
J Biol Chem 2003 Jan 6 [abstract on PubMed] [related articles]
Selected by | Jane Endicott
Evaluated 13 May 2003

X-ray structure of a voltage-dependent K+ channel.
Jiang Y, Lee A, …, Chait BT, MacKinnon R
Nature 2003 May 1 423(6935):33-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Barford / Jane Endicott / Christopher Miller / Manfred Schliwa / Jonathan Javitch
Evaluated 9 May 2003

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation.
Leng RP, Lin Y, …, Hakem R, Benchimol S
Cell 2003 Mar 21 112(6):779-91 [abstract on PubMed] [related articles] [order article]
Selected by | Jane Endicott
Evaluated 9 May 2003

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Yang H, Jeffrey PD, …, Lee WH, Pavletich NP
Science 2002 Sep 13 297(5588):1837-48 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ashok Venkitaraman / Kristina Downing / Jane Endicott / Stephen Jackson
Evaluated 20 Sep 2002

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