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Brent Iverson

No longer a member of F1000[ 06-JUL-2001 - 18-NOV-2008 ]
[ Homepage ] [ Evaluations ]
Home page

http://www.cm.utexas.edu/iverson/

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Evaluations

An empirical test of the concomitantly variable codon hypothesis.
Merlo LM, Lunzer M, Dean AM
Proc Natl Acad Sci U S A 2007 Jun 26 104(26):10938-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 13 Jul 2007

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution.
Bloom JD, Romero PA, Lu Z, Arnold FH
Biol Direct 2007 2:17 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson
Evaluated 13 Jul 2007

Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics.
Zimmermann J, Oakman EL, …, Boxer SG, Romesberg FE
Proc Natl Acad Sci U S A 2006 Sep 12 103(37):13722-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson
Evaluated 18 Sep 2006

Tapping diversity lost in transformations--in vitro amplification of ligation reactions.
Christ D, Famm K, Winter G
Nucleic Acids Res 2006 34(16):e108 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson
Evaluated 18 Sep 2006

Transcript-assisted transcriptional proofreading.
Zenkin N, Yuzenkova Y, Severinov K
Science 2006 Jul 28 313(5786):518-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson / Barry Stoddard / Gabriele Varani
Evaluated 21 Aug 2006

Stepwise growth of a single polymer chain.
Shin SH, Bayley H
J Am Chem Soc 2005 Aug 3 127(30):10462-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 19 Aug 2005

Engineering allosteric protein switches by domain insertion.
Ostermeier M
Protein Eng Des Sel 2005 Aug 18(8):359-64 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson
Evaluated 19 Aug 2005

Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection.
Künzler DE, Sasso S, …, Hilvert D, Kast P
J Biol Chem 2005 Sep 23 280(38):32827-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson / Mark Nelson
Evaluated 19 Aug 2005

Directed evolution of the promiscuous esterase activity of carbonic anhydrase II.
Gould SM, Tawfik DS
Biochemistry 2005 Apr 12 44(14):5444-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 6 May 2005

A structure-based database of antibody variable domain diversity.
Bond CJ, Wiesmann C, Marsters JC, Sidhu SS
J Mol Biol 2005 May 6 348(3):699-709 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 5 May 2005

Development and characterization of a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody that provides effective immunoprophylaxis in mice.
Greenough TC, Babcock GJ, …, Sullivan JL, Ambrosino DM
J Infect Dis 2005 Feb 15 191(4):507-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 4 Feb 2005

Discovering disease-associated enzymes by proteome reactivity profiling.
Barglow KT, Cravatt BF
Chem Biol 2004 Nov 11(11):1523-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 4 Jan 2005

Arresting cancer proliferation by small-molecule gene regulation.
Dickinson LA, Burnett R, …, Dervan PB, Gottesfeld JM
Chem Biol 2004 Nov 11(11):1583-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 4 Jan 2005

Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis.
Felding-Habermann B, Lerner RA, …, Saven A, Janda KD
Proc Natl Acad Sci U S A 2004 Dec 7 101(49):17210-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson
Evaluated 6 Dec 2004

X-ray snapshots of the maturation of an antibody response to a protein antigen.
Li Y, Li H, …, Smith-Gill SJ, Mariuzza RA
Nat Struct Biol 2003 Jun 10(6):482-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Colman / Brent Iverson
Evaluated 24 Jun 2003

Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library.
Cesaro-Tadic S, Lagos D, …, Blackburn GM, Plückthun A
Nat Biotechnol 2003 Jun 21(6):679-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Burckhard Seelig / Brent Iverson
Evaluated 24 Jun 2003

Long-range interactions stabilize the fold of a non-natural oligomer.
Cheng RP, DeGrado WF
J Am Chem Soc 2002 Oct 2 124(39):11564-5 [abstract on PubMed] [related articles] [order article]
Selected by | Brent Iverson
Evaluated 8 Oct 2002

Combinatorial mutagenesis to restrict amino acid usage in an enzyme to a reduced set.
Akanuma S, Kigawa T, Yokoyama S
Proc Natl Acad Sci U S A 2002 Oct 15 99(21):13549-53 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Brent Iverson / Mark Nelson
Evaluated 8 Oct 2002

Analysis of shuffled gene libraries.
Joern JM, Meinhold P, Arnold FH
J Mol Biol 2002 Feb 22 316(3):643-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson / Niles Lehman
Evaluated 12 Apr 2002

Folding-driven synthesis of oligomers.
Oh K, Jeong KS, Moore JS
Nature 2001 Dec 20-27 414(6866):889-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ross Weatherman / Brent Iverson
Evaluated 18 Jan 2002

A comparative analysis of the immunological evolution of antibody 28B4.
Yin J, Mundorff EC, …, Stevens RC, Schultz PG
Biochemistry 2001 Sep 11 40(36):10764-73 [abstract on PubMed] [related articles] [order article]
Selected by | Brent Iverson
Evaluated 4 Jan 2002

Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis.
Reetz MT, Wilensek S, Zha D, Jaeger KE
Angew Chem Int Ed Engl 2001 Oct 1 40(19):3589-3591 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brent Iverson
Evaluated 4 Jan 2002

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