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Christopher J Schofield
University of Oxford, OXford, United Kingdom

Faculty Member: CHEMICAL BIOLOGY > Biocatalysis [ since 24 April 2002 ]
[ Homepage ] [ Evaluations ]
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http://www.chem.ox.ac.uk/researchguide/cjschofield.html

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Evaluations

Solvent tuning of electrochemical potentials in the active sites of HiPIP versus ferredoxin.
Dey A, Jenney FE, …, Hedman B, Solomon EI
Science 2007 Nov 30 318(5855):1464-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Schofield
Evaluated 12 Dec 2007

Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Tan X, Calderon-Villalobos LI, …, Estelle M, Zheng N
Nature 2007 Apr 5 446(7136):640-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Schofield / Emmanuel Liscum / Anthony Means / Christian Hardtke / Tai-ping Sun / Seth J Davis
Evaluated 16 Apr 2007

Drugs, their targets and the nature and number of drug targets.
Imming P, Sinning C, Meyer A
Nat Rev Drug Discov 2006 Oct 5(10):821-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ron Magolda / Christopher Schofield
Evaluated 28 Nov 2006

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
Blasiak LC, Vaillancourt FH, Walsh CT, Drennan CL
Nature 2006 Mar 16 440(7082):368-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Schofield
Evaluated 22 Mar 2006

Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.
Chan DA, Sutphin PD, Yen SE, Giaccia AJ
Mol Cell Biol 2005 Aug 25(15):6415-26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Schofield
Evaluated 9 Sep 2005

The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4-hydroxylases.
van der Wel H, Ercan A, West CM
J Biol Chem 2005 Apr 15 280(15):14645-55 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Endicott / Christopher Schofield
Evaluated 25 Apr 2005

A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
Frank RA, Titman CM, …, Luisi BF, Perham RN
Science 2004 Oct 29 306(5697):872-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Schofield
Evaluated 2 Nov 2004

Histone deimination antagonizes arginine methylation.
Cuthbert GL, Daujat S, …, Bannister AJ, Kouzarides T
Cell 2004 Sep 3 118(5):545-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Julie Ahringer / Christopher Schofield / Robert Dutnall
Evaluated 20 Oct 2004

CD and MCD studies of the non-heme ferrous active site in (4-hydroxyphenyl)pyruvate dioxygenase: correlation between oxygen activation in the extradiol and alpha-KG-dependent dioxygenases.
Neidig ML, Kavana M, Moran GR, Solomon EI
J Am Chem Soc 2004 Apr 14 126(14):4486-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Schofield
Evaluated 19 Apr 2004

Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.
Berkovitch F, Nicolet Y, …, Jarrett JT, Drennan CL
Science 2004 Jan 2 303(5654):76-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Schofield / Rowena Matthews / Joan Broderick / Mark Nelson
Evaluated 14 Jan 2004

Oxygen and iron regulation of iron regulatory protein 2.
Hanson ES, Rawlins ML, Leibold EA
J Biol Chem 2003 Oct 10 278(41):40337-42 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan Gleadle / Christopher Schofield
Evaluated 15 Aug 2003

The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya.
Núñez LE, Méndez C, …, Blanco G, Salas JA
Chem Biol 2003 Apr 10(4):301-11 [abstract on PubMed] [related articles] [order article]
Selected by | Christopher Schofield
Evaluated 20 Jun 2003

Crystallographic and spectroscopic characterization of a nonheme Fe(IV)-O complex.
Rohde JU, In JH, …, Nam W, Que L
Science 2003 Feb 14 299(5609):1037-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Broderick / Marc Fontecave / Christopher Schofield
Evaluated 24 Mar 2003

Identification, characterization, and regulation of a cluster of genes involved in carbapenem biosynthesis in Photorhabdus luminescens.
Derzelle S, Duchaud E, …, Danchin A, Bertin P
Appl Environ Microbiol 2002 Aug 68(8):3780-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Schofield
Evaluated 1 Nov 2002

Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution.
Anand R, Dorrestein PC, …, Begley TP, Ealick SE
Biochemistry 2002 Jun 18 41(24):7659-69 [abstract on PubMed] [related articles] [order article]
Selected by | Christopher Schofield
Evaluated 12 Aug 2002

Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.
Hansson LO, Friedler A, …, Rudiger S, Fersht AR
Proc Natl Acad Sci U S A 2002 Aug 6 99(16):10305-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Schofield
Evaluated 9 Aug 2002

The catalytic pathway of horseradish peroxidase at high resolution.
Berglund GI, Carlsson GH, …, Henriksen A, Hajdu J
Nature 2002 May 23 417(6887):463-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carola Hunte / Christopher Schofield / Kristina Downing
Evaluated 19 Jun 2002

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
Dames SA, Martinez-Yamout M, …, Dyson HJ, Wright PE
Proc Natl Acad Sci U S A 2002 Apr 16 99(8):5271-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Wolfgang Jahnke / Robert Dutnall / Christopher Schofield
Evaluated 11 Jun 2002

Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene.
Zhou J, Rocklin AM, …, Que L, Solomon EI
J Am Chem Soc 2002 May 1 124(17):4602-9 [abstract on PubMed] [related articles] [order article]
Selected by | Christopher Schofield / Mark Nelson
Evaluated 13 May 2002

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