homefeedbacksupportlog on 6-Sep-2008 
  About F1000

 What is F1000 Biology?
 Key features
 How it's organized
 FAQs
 Faculties and sections
 Scope of sections
 List of Faculty Members
 The evaluation system
 Citing F1000
 Take a tour of the site
 Accessing fulltexts
 PubMed linkout
 How to subscribe
 Academic subscriptions
 Corporate subscriptions
 Try F1000 for free
 Who we are
 Media information
 Librarian resources
 Press releases
 In the press
 Developing countries
 F1000 Medicine
 Terms and conditions
 Privacy policy
 Contact us


Steven A. Rosenzweig
Department of Pharmacology, Medical University of South Carolina, Charleston, United States of America

Faculty Member: Physiology > Endocrinology [ since 24 March 2005 ]
[ Homepage ] [ Evaluations ]
Home page

http://www2.musc.edu/pharm/rosenzweig.html

to email [Help]
Evaluations

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Huang X, Wullschleger S, …, Fleming S, Alessi DR
Biochem J 2008 Jun 1 412(2):211-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig / Alex Toker
Evaluated 14 May 2008

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.
Khan EM, Lanir R, Danielson AR, Goldkorn T
FASEB J 2008 Mar 22(3):910-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 4 Mar 2008

Engineering insulin-like growth factor-1 for local delivery.
Tokunou T, Miller R, …, Grodzinsky AJ, Lee RT
FASEB J 2008 Feb 19:Published online before print [full text]
Selected by | Steven A. Rosenzweig
Evaluated 22 Feb 2008

Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria.
Leu JI, George DL
Genes Dev 2007 Dec 1 21(23):3095-109 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 4 Jan 2008

Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Kaneda A, Wang CJ, …, Levchenko A, Feinberg AP
Proc Natl Acad Sci U S A 2007 Dec 26 104(52):20926-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 21 Dec 2007

Insulin receptor substrate-1 is an important mediator of ovarian cancer cell growth suppression by all-trans retinoic acid.
Ravikumar S, Perez-Liz G, …, Soprano DR, Soprano KJ
Cancer Res 2007 Oct 1 67(19):9266-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 11 Oct 2007

Brain IRS2 signaling coordinates life span and nutrient homeostasis.
Taguchi A, Wartschow LM, White MF
Science 2007 Jul 20 317(5836):369-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 1 Aug 2007

Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
Ball SG, Shuttleworth CA, Kielty CM
J Cell Biol 2007 May 7 177(3):489-500 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul Bornstein / Steven A. Rosenzweig
Evaluated 22 May 2007

Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24.
Fukushima T, Tezuka T, …, Nakano S, Kataoka H
J Biol Chem 2007 Jun 22 282(25):18634-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 14 May 2007

Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage.
Kang SG, Brown AL, Chung JH
J Biol Chem 2007 Mar 2 282(9):6090-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 19 Mar 2007

Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.
Sutton KM, Hayat S, …, Yang J, Ashcroft M
Oncogene 2007 Jun 7 26(27):3920-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven A. Rosenzweig
Evaluated 25 Jan 2007

Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration.
Cui X, Kim HJ, …, Brown PH, Lee AV
Cancer Res 2006 May 15 66(10):5304-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig
Evaluated 3 Aug 2006

Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms.
Silha JV, Sheppard PC, …, Dodd JG, Murphy LJ
Endocrinology 2006 May 147(5):2112-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig
Evaluated 5 May 2006

Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells.
Akekawatchai C, Holland JD, …, Wallace JC, McColl SR
J Biol Chem 2005 Dec 2 280(48):39701-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig
Evaluated 7 Dec 2005

Structure and properties of the C-terminal domain of insulin-like growth factor-binding protein-1 isolated from human amniotic fluid.
Sala A, Capaldi S, …, Galliano M, Monaco HL
J Biol Chem 2005 Aug 19 280(33):29812-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig
Evaluated 17 Aug 2005

Synthesis of the blood circulating C-terminal fragment of insulin-like growth factor (IGF)-binding protein-4 in its native conformation. Crystallization, heparin and IGF binding, and osteogenic activity.
Fernández-Tornero C, Lozano RM, …, Romero A, Giménez-Gallego G
J Biol Chem 2005 May 13 280(19):18899-907 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steven A. Rosenzweig
Evaluated 12 May 2005

^Top  Back to Faculty Members


© 1999-2008 Biology Reports Ltd unless otherwise stated < info@f1000.com >   Terms and conditions   Legal info