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Jonathon Pines
Wellcome/CR UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

Faculty Member: CELL BIOLOGY > Cell growth & division [ since 24 August 2001 ]
[ Evaluations ]
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Evaluations

Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
Nakano M, Cardinale S, …, Earnshaw WC, Masumoto H
Dev Cell 2008 Apr 14(4):507-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 23 Apr 2008

Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells.
Lee J, Kitajima TS, …, Miyake M, Watanabe Y
Nat Cell Biol 2008 Jan 10(1):42-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 12 Mar 2008

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges.
Chan KL, North PS, Hickson ID
EMBO J 2007 Jul 25 26(14):3397-409 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 17 Jul 2007

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.
Li M, York JP, Zhang P
Mol Cell Biol 2007 May 27(9):3481-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 8 Jun 2007

Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.
Dubreuil V, Marzesco AM, …, Huttner WB, Wilsch-Bräuninger M
J Cell Biol 2007 Feb 12 176(4):483-95 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 6 Mar 2007

Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Hutterer A, Berdnik D, …, Schleiffer A, Knoblich JA
Dev Cell 2006 Aug 11(2):147-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 18 Aug 2006

Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts.
Yu J, Zhao Y, …, Galas S, Goldberg ML
Mol Cell 2006 Apr 7 22(1):83-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines / Iain Hagan
Evaluated 20 Apr 2006

Fast complementation of split fluorescent protein triggered by DNA hybridization.
Demidov VV, Dokholyan NV, …, Cantor CR, Broude NE
Proc Natl Acad Sci U S A 2006 Feb 14 103(7):2052-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 16 Feb 2006

Swe1p responds to cytoskeletal perturbation, not bud size, in S. cerevisiae.
McNulty JJ, Lew DJ
Curr Biol 2005 Dec 20 15(24):2190-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 11 Jan 2006

NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry.
Bassermann F, von Klitzing C, …, Peschel C, Duyster J
Cell 2005 Jul 15 122(1):45-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 20 Jul 2005

p90Rsk is not involved in cytostatic factor arrest in mouse oocytes.
Dumont J, Umbhauer M, …, Hanauer A, Verlhac MH
J Cell Biol 2005 Apr 25 169(2):227-31 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 28 Apr 2005

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs.
Tung JJ, Hansen DV, …, Adler JR, Jackson PK
Proc Natl Acad Sci U S A 2005 Mar 22 102(12):4318-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 18 Mar 2005

Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity.
Schmidt A, Duncan PI, …, Nigg EA, Mayer TU
Genes Dev 2005 Feb 15 19(4):502-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 18 Mar 2005

DNA replication checkpoint control of Wee1 stability by vertebrate Hsl7.
Yamada A, Duffy B, Perry JA, Kornbluth S
J Cell Biol 2004 Dec 6 167(5):841-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 4 Jan 2005

Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control.
Mimura S, Seki T, Tanaka S, Diffley JF
Nature 2004 Oct 28 431(7012):1118-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Endicott / Gennaro D'Urso / Jonathon Pines
Evaluated 15 Dec 2004

Emi1-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest.
Ohsumi K, Koyanagi A, …, Gotoh T, Kishimoto T
Proc Natl Acad Sci U S A 2004 Aug 24 101(34):12531-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Angel Nebreda / Jonathon Pines
Evaluated 1 Sep 2004

Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".
Uetake Y, Sluder G
J Cell Biol 2004 Jun 7 165(5):609-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines / Conly Rieder / William Sullivan
Evaluated 13 Jul 2004

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis.
van Vugt MA, van de Weerdt BC, …, Wolthuis RM, Medema RH
J Biol Chem 2004 Aug 27 279(35):36841-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 5 Jul 2004

Requirements of cyclin a for mitosis are independent of its subcellular localization.
Dienemann A, Sprenger F
Curr Biol 2004 Jun 22 14(12):1117-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 5 Jul 2004

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.
Watanabe N, Arai H, …, Hunter T, Osada H
Proc Natl Acad Sci U S A 2004 Mar 30 101(13):4419-24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 28 Apr 2004

Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts.
Yamano H, Gannon J, Mahbubani H, Hunt T
Mol Cell 2004 Jan 16 13(1):137-47 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathon Pines / Kevin Hardwick
Evaluated 30 Jan 2004

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells.
Hirota T, Kunitoku N, …, Hatakeyama K, Saya H
Cell 2003 Sep 5 114(5):585-98 [abstract on PubMed] [related articles] [order article]
Selected by | Tomoyuki Tanaka / Valeri Vasioukhin
Dissenters | Jonathon Pines
Author Response | Hideyuki Saya
Evaluated 30 Sep 2003


The Ran GTPase regulates kinetochore function.
Arnaoutov A, Dasso M
Dev Cell 2003 Jul 5(1):99-111 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathon Pines / Claire Walczak
Evaluated 31 Jul 2003

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.
Passmore LA, McCormack EA, …, Harper JW, Barford D
EMBO J 2003 Feb 17 22(4):786-96 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 13 Feb 2003

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.
Babu JR, Jeganathan KB, …, Kang-Decker N, van Deursen JM
J Cell Biol 2003 Feb 3 160(3):341-53 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines / Timothy Yen
Evaluated 4 Feb 2003

Addition of a photocrosslinking amino acid to the genetic code of Escherichiacoli.
Chin JW, Martin AB, …, Wang L, Schultz PG
Proc Natl Acad Sci U S A 2002 Aug 20 99(17):11020-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karin Romisch / Jonathon Pines
Evaluated 27 Aug 2002

Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1.
Peter M, Le Peuch C, …, Donoghue DJ, Dorée M
EMBO Rep 2002 Jun 3(6):551-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines
Evaluated 7 Jun 2002

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells.
Meraldi P, Honda R, Nigg EA
EMBO J 2002 Feb 15 21(4):483-92 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathon Pines / Joan Ruderman / Sergio Moreno / David Glover / David Morgan / William Earnshaw
Evaluated 15 Feb 2002

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering.
Zhang J, Ma Y, Taylor SS, Tsien RY
Proc Natl Acad Sci U S A 2001 Dec 18 98(26):14997-5002 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathon Pines / Atsushi Miyawaki / Tullio Pozzan
Evaluated 8 Jan 2002

Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.
Ting AY, Kain KH, Klemke RL, Tsien RY
Proc Natl Acad Sci U S A 2001 Dec 18 98(26):15003-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Nancy Allbritton / Jonathon Pines / Tullio Pozzan / Deirdre Meldrum
Evaluated 8 Jan 2002

Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.
Schwab M, Neutzner M, Möcker D, Seufert W
EMBO J 2001 Sep 17 20(18):5165-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Frederick R. Cross / Jonathon Pines
Evaluated 1 Nov 2001

The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner.
Hilioti Z, Chung YS, …, Hardy CF, Cohen-Fix O
Curr Biol 2001 Sep 4 11(17):1347-52 [abstract on PubMed] [related articles] [order article]
Selected by | Steven Reed / Frederick R. Cross / Jonathon Pines / Jeffrey Wade Harper
Evaluated 1 Nov 2001

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