Kelly A. Frazer is Senior Scientist and head of the cross-species program at Perlegen Sciences. She received her Ph.D. degree from the Biomedical Sciences program at the University of California, San Francisco and then was a postdoctoral fellow in the Genome Science Department of LBNL. There she utilized comparative analyses of human and mouse sequences coupled with transgenesis studies to discover and characterize evolutionarily conserved noncoding elements. Dr. Frazer''s current research interest includes comparative genomics, and understanding patterns of single nucleotide human variation.

Comparative analyses of multi-species sequences from targeted genomic regions. Thomas JW, Touchman JW, …, Miller W, Green ED Nature 2003 Aug 14 424(6950):788-93 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Kelly Frazer / David B. Goldstein Evaluated 8 Sep 2003 Distinguishing regulatory DNA from neutral sites. Elnitski L, Hardison RC, …, Miller W, Chiaromonte F Genome Res 2003 Jan 13(1):64-72 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jeremy Buhler / Kelly Frazer Evaluated 3 Mar 2003 Genetic dissection of transcriptional regulation in budding yeast. Brem RB, Yvert G, Clinton R, Kruglyak L Science 2002 Apr 26 296(5568):752-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Kelly Frazer Evaluated 18 Jul 2002 Utility and distribution of conserved noncoding sequences in the grasses. Kaplinsky NJ, Braun DM, …, Goff SA, Freeling M Proc Natl Acad Sci U S A 2002 Apr 30 99(9):6147-51 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elizabeth Kellogg / Kelly Frazer / Detlef Weigel Evaluated 11 Jun 2002 Construction and analysis of a human-chimpanzee comparative clone map. Fujiyama A, Watanabe H, …, Hattori M, Sakaki Y Science 2002 Jan 4 295(5552):131-4 [abstract on PubMed] [related articles] [FREE full text] Selected by | Kelly Frazer Evaluated 21 Jan 2002 Great ape DNA sequences reveal a reduced diversity and an expansion in humans. Kaessmann H, Wiebe V, Weiss G, Pääbo S Nat Genet 2001 Feb 27(2):155-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Kelly Frazer Evaluated 26 Oct 2001 An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Pennacchio LA, Olivier M, …, Krauss RM, Rubin EM Science 2001 Oct 5 294(5540):169-73 [abstract on PubMed] [related articles] [FREE full text] Selected by | Kelly Frazer / Deborah Nickerson Evaluated 25 Oct 2001 Evidence for stabilizing selection in a eukaryotic enhancer element. Ludwig MZ, Bergman C, Patel NH, Kreitman M Nature 2000 Feb 3 403(6769):564-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Kelly Frazer / Thomas Mitchell-Olds Evaluated 19 Oct 2001 Analysis of conserved noncoding DNA in Drosophila reveals similar constraints in intergenic and intronic sequences. Bergman CM, Kreitman M Genome Res 2001 Aug 11(8):1335-45 [abstract on PubMed] [related articles] [FREE full text] Selected by | Kelly Frazer Evaluated 19 Oct 2001 Computational identification of noncoding RNAs in E. coli by comparative genomics. Rivas E, Klein RJ, Jones TA, Eddy SR Curr Biol 2001 Sep 4 11(17):1369-73 [abstract on PubMed] [related articles] [order article] Selected by | Kelly Frazer / Bruno Sobral / Webb Miller Evaluated 18 Oct 2001

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