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Charles Streuli
School of Biological Sciences, University of Manchester, Manchester, United Kingdom

Faculty Member: Cell Biology > Cell Adhesion [ since 4 July 2001 ]
[ Homepage ] [ Evaluations ]
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http://www.ls.manchester.ac.uk/people/profile/index.asp?id=447

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Evaluations

Endogenous activation patterns of Cdc42 GTPase within Drosophila embryos.
Kamiyama D, Chiba A
Science 2009 Jun 5 324(5932):1338-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 15 Jun 2009

Polarized fluid movement and not cell death, creates luminal spaces in adult prostate epithelium.
Pearson JF, Hughes S, Chambers K, Lang SH
Cell Death Differ 2009 Mar 16(3):475-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 10 Mar 2009


One-dimensional topography underlies three-dimensional fibrillar cell migration.
Doyle AD, Wang FW, Matsumoto K, Yamada KM
J Cell Biol 2009 Feb 23 184(4):481-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Egelhoff / Charles Streuli / Martin Humphries / Martin A. Schwartz
Evaluated 9 Mar 2009

Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function.
Xu R, Nelson CM, …, Vonderhaar BK, Bissell MJ
J Cell Biol 2009 Jan 12 184(1):57-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 30 Jan 2009

Novel egg white-based 3-D cell culture system.
Abraham Kaipparettu B, Kuiatse I, …, Lee AV, Oesterreich S
Biotechniques 2008 Aug 45(2):165-8, 170-1 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Jonathan Chernoff
Evaluated 18 Aug 2008

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells.
Taddei I, Deugnier MA, …, Thiery JP, Glukhova MA
Nat Cell Biol 2008 Jun 10(6):716-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 10 Jun 2008

SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis.
Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T
Nature 2008 Mar 13 452(7184):187-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ulf Pettersson / Dinah Singer / Charles Streuli
Evaluated 14 May 2008

Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis.
Ewald AJ, Brenot A, …, Chan BS, Werb Z
Dev Cell 2008 Apr 14(4):570-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 14 May 2008

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.
King N, Westbrook MJ, …, Grigoriev IV, Rokhsar D
Nature 2008 Feb 14 451(7180):783-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Max Telford / Rafael Zardoya / Charles Streuli / Laura Landweber / Joe Heitman
Evaluated 4 Apr 2008

Endogenous human microRNAs that suppress breast cancer metastasis.
Tavazoie SF, Alarcón C, …, Gerald WL, Massagué J
Nature 2008 Jan 10 451(7175):147-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dinah Singer / Martine Roussel / Charles Streuli
Evaluated 26 Feb 2008

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth.
Roarty K, Serra R
Development 2007 Nov 134(21):3929-39 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 8 Feb 2008

Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells.
Pearson GW, Hunter T
J Cell Biol 2007 Dec 31 179(7):1555-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Friedemann Kiefer
Evaluated 16 Jan 2008

The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways.
Bourgin C, Murai KK, Richter M, Pasquale EB
J Cell Biol 2007 Sep 24 178(7):1295-307 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 7 Nov 2007

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
Ma L, Teruya-Feldstein J, Weinberg RA
Nature 2007 Oct 11 449(7163):682-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Cole / Charles Streuli / Günter Mayer
Evaluated 5 Nov 2007


Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function.
Kren A, Baeriswyl V, …, Cavallaro U, Christofori G
EMBO J 2007 Jun 20 26(12):2832-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 27 Jul 2007

Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.
Holst F, Stahl PR, …, Sauter G, Simon R
Nat Genet 2007 May 39(5):655-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 3 May 2007

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.
Ciarloni L, Mallepell S, Brisken C
Proc Natl Acad Sci U S A 2007 Mar 27 104(13):5455-60 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 17 Apr 2007


Restoration of p53 function leads to tumour regression in vivo.
Ventura A, Kirsch DG, …, Weissleder R, Jacks T
Nature 2007 Feb 8 445(7128):661-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Vile / Charles Streuli
Evaluated 14 Mar 2007

Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models.
Rajkumar L, Kittrell FS, …, Nandi S, Medina D
Breast Cancer Res 2007 9(1):R12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 6 Mar 2007

Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist.
Poole AJ, Li Y, …, Lee WH, Lee EY
Science 2006 Dec 1 314(5804):1467-70 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Takashi Tsuruo / Charles Streuli
Evaluated 1 Mar 2007


The consensus coding sequences of human breast and colorectal cancers.
Sjöblom T, Jones S, …, Kinzler KW, Velculescu VE
Science 2006-09-07 314(5797):268-74 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Channing Der / Chris Sander / Karin Schmitt / Charles Streuli / Kai Zinn / Robert Copeland
Evaluated 13 Nov 2006


Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
Ayyanan A, Civenni G, …, Dotto GP, Brisken C
Proc Natl Acad Sci U S A 2006 Mar 7 103(10):3799-804 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 6 Oct 2006

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.
Guo W, Pylayeva Y, …, Inghirami G, Giancotti FG
Cell 2006 Aug 11 126(3):489-502 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Dalton / Avri Ben-Ze'ev / Charles Streuli
Evaluated 6 Oct 2006

Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo.
Park CC, Zhang H, …, Park CJ, Bissell MJ
Cancer Res 2006 Feb 1 66(3):1526-35 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul Bornstein / Charles Streuli
Evaluated 30 Jun 2006

A pooled analysis of bone marrow micrometastasis in breast cancer.
Braun S, Vogl FD, …, Vincent-Salomon A, Pantel K
N Engl J Med 2005 Aug 25 353(8):793-802 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 7 Mar 2006

Generation of a functional mammary gland from a single stem cell.
Shackleton M, Vaillant F, …, Lindeman GJ, Visvader JE
Nature 2006 Jan 5 439(7072):84-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giovanni Neri / Charles Streuli / Martine Roussel / Peter Hartmann / Matthew John Smalley
Evaluated 7 Mar 2006


Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice.
Ewan KB, Oketch-Rabah HA, …, Moses HL, Barcellos-Hoff MH
Am J Pathol 2005 Aug 167(2):409-17 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 19 Jan 2006

The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts.
Todorovicç V, Chen CC, Hay N, Lau LF
J Cell Biol 2005 Nov 7 171(3):559-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli / Kenneth Yamada
Evaluated 25 Nov 2005

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.
Hakem A, Sanchez-Sweatman O, …, Khokha R, Mak TW
Genes Dev 2005 Sep 1 19(17):1974-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ron Prywes / Charles Streuli
Evaluated 4 Nov 2005

The transcriptional repressor Snail promotes mammary tumor recurrence.
Moody SE, Perez D, …, Cardiff RD, Chodosh LA
Cancer Cell 2005 Sep 8(3):197-209 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Avri Ben-Ze'ev / Frans Van Roy
Evaluated 4 Nov 2005


The extracellular matrix guides the orientation of the cell division axis.
Théry M, Racine V, …, Sibarita JB, Bornens M
Nat Cell Biol 2005 Oct 7(10):947-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Buzz Baum
Evaluated 21 Oct 2005

Genes that mediate breast cancer metastasis to lung.
Minn AJ, Gupta GP, …, Gerald WL, Massagué J
Nature 2005 Jul 28 436(7050):518-24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anthony Means / Celerino Abad-Zapatero / Kenneth Yamada / Jenny Ting / Charles Streuli
Evaluated 5 Sep 2005

Colorectal cancer: mutations in a signalling pathway.
Parsons DW, Wang TL, …, Lengauer C, Velculescu VE
Nature 2005 Aug 11 436(7052):792 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 5 Sep 2005

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis.
Shen TL, Park AY, …, Gu H, Guan JL
J Cell Biol 2005 Jun 20 169(6):941-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 11 Jul 2005

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.
MacKeigan JP, Murphy LO, Blenis J
Nat Cell Biol 2005 Jun 7(6):591-600 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ron Prywes / Michael B. Yaffe / Charles Streuli
Evaluated 4 Jul 2005

Visualizing the mechanical activation of Src.
Wang Y, Botvinick EL, …, Tsien RY, Chien S
Nature 2005 Apr 21 434(7036):1040-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kenneth Yamada / Etienne Joly / Charles Streuli
Evaluated 16 May 2005

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
Mattila E, Pellinen T, …, Arjonen A, Ivaska J
Nat Cell Biol 2005 Jan 7(1):78-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 13 May 2005

Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition.
Abell K, Bilancio A, …, Vanhaesebroeck B, Watson CJ
Nat Cell Biol 2005 Apr 7(4):392-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 29 Apr 2005

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP.
Sabeh F, Ota I, …, Chung D, Weiss SJ
J Cell Biol 2004 Nov 22 167(4):769-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kenneth Yamada / Charles Streuli
Evaluated 24 Mar 2005

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone.
Williams CC, Allison JG, …, Marrero L, Jones FE
J Cell Biol 2004 Nov 8 167(3):469-78 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 8 Mar 2005

Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland.
Morroni M, Giordano A, …, Marelli M, Cinti S
Proc Natl Acad Sci U S A 2004 Nov 30 101(48):16801-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 21 Dec 2004

Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis.
Ishibe S, Joly D, Liu ZX, Cantley LG
Mol Cell 2004 Oct 22 16(2):257-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin A. Schwartz / Charles Streuli
Evaluated 18 Nov 2004

Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis.
Janes SM, Watt FM
J Cell Biol 2004 Aug 2 166(3):419-31 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 13 Sep 2004

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.
White DE, Kurpios NA, …, Mueller U, Muller WJ
Cancer Cell 2004 Aug 6(2):159-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Filippo Giancotti
Evaluated 2 Sep 2004

Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling.
Murtagh J, McArdle E, …, Furlong F, Martin F
J Cell Biol 2004 Jul 5 166(1):133-43 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 26 Jul 2004

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.
Paez JG, Jänne PA, …, Johnson BE, Meyerson M
Science 2004 Jun 4 304(5676):1497-500 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Kaelin / Patricia C Weber / Joachim Herz / Charles Streuli / Alfred Wittinghofer / Charles Brenner
Evaluated 1 Jul 2004

Conformational control of Bax localization and apoptotic activity by Pro168.
Schinzel A, Kaufmann T, …, Grubb D, Borner C
J Cell Biol 2004 Mar 29 164(7):1021-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 5 May 2004

Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction.
Lidke DS, Nagy P, …, Jares-Erijman EA, Jovin TM
Nat Biotechnol 2004 Feb 22(2):198-203 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brett Adams / Charles Streuli
Evaluated 29 Mar 2004

Integrins regulate Rac targeting by internalization of membrane domains.
del Pozo MA, Alderson NB, …, Anderson RG, Schwartz MA
Science 2004 Feb 6 303(5659):839-42 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Valeri Vasioukhin / Robert Parton / Kermit Carraway / Anna Huttenlocher / Martin Humphries / Charles Streuli
Evaluated 25 Mar 2004

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.
Webb DJ, Donais K, …, Parsons JT, Horwitz AF
Nat Cell Biol 2004 Feb 6(2):154-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean-Antoine Girault / Charles Streuli / Thomas Egelhoff
Evaluated 11 Mar 2004

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Hughes-Davies L, Huntsman D, …, Caldas C, Kouzarides T
Cell 2003 Nov 26 115(5):523-35 [abstract on PubMed] [related articles] [order article]
Selected by | Charles Streuli
Evaluated 11 Feb 2004

Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration.
Yebra M, Montgomery AM, …, Tessier-Lavigne M, Cirulli V
Dev Cell 2003 Nov 5(5):695-707 [abstract on PubMed] [related articles] [order article]
Selected by | Chaya Kalcheim / Charles Streuli / Orly Reiner
Evaluated 12 Dec 2003

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins.
Kim M, Carman CV, Springer TA
Science 2003 Sep 19 301(5640):1720-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael Dustin / Klaus Ley / Kermit Carraway / Peter Ekblom / Jean Schwarzbauer / Charles Streuli
Evaluated 28 Oct 2003

Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix.
Hotary KB, Allen ED, …, Long MW, Weiss SJ
Cell 2003 Jul 11 114(1):33-45 [abstract on PubMed] [related articles] [order article]
Selected by | Kenneth Yamada / Charles Streuli
Evaluated 23 Sep 2003

A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland.
Kritikou EA, Sharkey A, …, Clarkson RW, Watson CJ
Development 2003 Aug 130(15):3459-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 8 Aug 2003

PKCepsilon is a permissive link in integrin-dependent IFN-gamma signalling that facilitates JAK phosphorylation of STAT1.
Ivaska J, Bosca L, Parker PJ
Nat Cell Biol 2003 Apr 5(4):363-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Humphries / Charles Streuli
Evaluated 23 Apr 2003

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor.
Vermeer PD, Einwalter LA, …, Zabner J, Welsh MJ
Nature 2003 Mar 20 422(6929):322-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michel Labouesse / Ben Zion Shilo / Charles Streuli / Surender Kharbanda / Sally Temple / Steven Burden
Evaluated 22 Apr 2003

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.
Dajee M, Lazarov M, …, Kubo Y, Khavari PA
Nature 2003 Feb 6 421(6923):639-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli / Jean Schwarzbauer / Arthur Mercurio / Channing Der
Evaluated 5 Mar 2003

ERK1 associates with alpha(v)beta 3 integrin and regulates cell spreading on vitronectin.
Roberts MS, Woods AJ, Shaw PE, Norman JC
J Biol Chem 2003 Jan 17 278(3):1975-85 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 31 Jan 2003

14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax.
Nomura M, Shimizu S, …, Matsuda H, Tsujimoto Y
J Biol Chem 2003 Jan 17 278(3):2058-65 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 31 Jan 2003

CNS integrins switch growth factor signalling to promote target-dependent survival.
Colognato H, Baron W, …, Georges-Labouesse E, ffrench-Constant C
Nat Cell Biol 2002 Nov 4(11):833-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ed Manser / Christopher Marshall / Charles Streuli
Evaluated 2 Jan 2003

E-cadherin is a survival factor for the lactating mouse mammary gland.
Boussadia O, Kutsch S, …, Delmas V, Kemler R
Mech Dev 2002 Jul 115(1-2):53-62 [abstract on PubMed] [related articles] [order article]
Selected by | Charles Streuli
Evaluated 28 Nov 2002

Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice.
Tonner E, Barber MC, …, Whitelaw CB, Flint DJ
Development 2002 Oct 129(19):4547-57 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 28 Nov 2002

Perturbation of beta1-integrin function in involuting mammary gland results in premature dedifferentiation of secretory epithelial cells.
Faraldo MM, Deugnier MA, …, Thiery JP, Glukhova MA
Mol Biol Cell 2002 Oct 13(10):3521-31 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 28 Nov 2002

Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland.
Welm BE, Freeman KW, …, Spencer DM, Rosen JM
J Cell Biol 2002 May 13 157(4):703-14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 19 Jul 2002

Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain.
Hirsch E, Barberis L, …, Fässler R, Altruda F
J Cell Biol 2002 Apr 29 157(3):481-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carol Otey / Charles Streuli
Evaluated 12 Jul 2002

Tumor regression by targeted gene delivery to the neovasculature.
Hood JD, Bednarski M, …, Xiang R, Cheresh DA
Science 2002 Jun 28 296(5577):2404-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ulf Pettersson / Charles Streuli / Kermit Carraway / Chandra Kumar / Martin Humphries
Evaluated 12 Jul 2002

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI.
Del Pozo MA, Kiosses WB, …, Hahn KM, Schwartz MA
Nat Cell Biol 2002 Mar 4(3):232-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Couchman / Kristiina Vuori / Denise Montell / Martin Humphries / Charles Streuli
Evaluated 17 Jun 2002

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.
Willem M, Miosge N, …, Timpl R, Mayer U
Development 2002 Jun 129(11):2711-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 17 Jun 2002

C-cadherin ectodomain structure and implications for cell adhesion mechanisms.
Boggon TJ, Murray J, …, Gumbiner BM, Shapiro L
Science 2002 May 17 296(5571):1308-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robert Liddington / Vance Lemmon / Carlos Ibanez / Charles Streuli / Jia-huai Wang / David Stokes
Evaluated 6 Jun 2002

Taking cell-matrix adhesions to the third dimension.
Cukierman E, Pankov R, Stevens DR, Yamada KM
Science 2001 Nov 23 294(5547):1708-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Martin Humphries / Anna Huttenlocher / Dafna Bar-Sagi / Charles Streuli
Evaluated 14 Mar 2002

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development.
Cao Y, Bonizzi G, …, Schmidt EV, Karin M
Cell 2001 Dec 14 107(6):763-75 [abstract on PubMed] [related articles] [order article]
Selected by | Charles Streuli
Evaluated 22 Feb 2002

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin.
Hayashi I, Vuori K, Liddington RC
Nat Struct Biol 2002 Feb 9(2):101-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Stokes / Charles Streuli / Michael Eck / Michael Schaller
Evaluated 20 Feb 2002

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini.
Muthuswamy SK, Li D, …, Bissell MJ, Brugge JS
Nat Cell Biol 2001 Sep 3(9):785-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 15 Oct 2001

Specific protection against breast cancers by cyclin D1 ablation.
Yu Q, Geng Y, Sicinski P
Nature 2001 Jun 28 411(6841):1017-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Streuli
Evaluated 11 Oct 2001

Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression.
Carrano AC, Pagano M
J Cell Biol 2001 Jun 25 153(7):1381-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Charles Streuli
Evaluated 4 Oct 2001

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