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Paul J. Lehner
Department of Immunology, The Cambridge Institute for Medical Research, Cambridge, United Kingdom

Faculty Member: Immunology > Antigen Processing & Recognition [ since 1 March 2002 ]
[ Homepage ] [ Evaluations ]
Home page

http://www.cimr.cam.ac.uk/investigators/lehner/profile.html

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Evaluations

TrkA Receptor Endolysosomal Degradation is both Ubiquitin and Proteasome Dependent.
Geetha T, Wooten MW
Traffic 2008 Apr 18 0 [abstract on PubMed] [related articles] [full text]
Selected by | Paul J. Lehner
Evaluated 9 May 2008

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.
Kirkpatrick DS, Hathaway NA, …, King RW, Gygi SP
Nat Cell Biol 2006 Jul 8(7):700-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul J. Lehner
Evaluated 25 Aug 2006

Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation.
Blachère NE, Darnell RB, Albert ML
PLoS Biol 2005 Jun 3(6):e185 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Caetano Reis e Sousa / Paul J. Lehner
Evaluated 27 Jun 2005

Unanticipated antigens: translation initiation at CUG with leucine.
Schwab SR, Shugart JA, …, Malarkannan S, Shastri N
PLoS Biol 2004 Nov 2(11):e366 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul J. Lehner
Evaluated 22 Dec 2004

A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7.
Canning M, Boutell C, Parkinson J, Everett RD
J Biol Chem 2004 Sep 10 279(37):38160-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul J. Lehner
Evaluated 28 Jul 2004

Peptides induce ATP hydrolysis at both subunits of the transporter associated with antigen processing.
Chen M, Abele R, Tampé R
J Biol Chem 2003 Aug 8 278(32):29686-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul J. Lehner
Evaluated 9 Jul 2003

Transfer of GRP94(Gp96)-associated peptides onto endosomal MHC class I molecules.
Berwin B, Rosser MF, Brinker KG, Nicchitta CV
Traffic 2002 May 3(5):358-66 [abstract on PubMed] [related articles] [order article]
Selected by | Paul J. Lehner
Evaluated 27 Aug 2002

Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides.
Berwin B, Hart JP, Pizzo SV, Nicchitta CV
J Immunol 2002 May 1 168(9):4282-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul J. Lehner
Evaluated 1 May 2002

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins.
Polo S, Sigismund S, …, De Camilli P, Di Fiore PP
Nature 2002 Mar 28 416(6879):451-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul J. Lehner / Tom Rapoport
Evaluated 16 Apr 2002

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates.
Bishop N, Horman A, Woodman P
J Cell Biol 2002 Apr 1 157(1):91-101 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul J. Lehner / Elizabeth Smythe
Evaluated 15 Apr 2002

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