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David Alpers
Department of Medicine, Washington University School of Medicine, St Louis, United States of America

Faculty Member: Physiology > Gastrointestinal Physiology [ since 11 January 2005 ]
[ Evaluations ]
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Evaluations

Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth.
Lee JH, Karamychev VN, …, Weimer B, O'Sullivan DJ
BMC Genomics 2008 9:247 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Claire Shearman / Frank Robb / David Alpers
Evaluated 11 Aug 2008

Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C.
Montel-Hagen A, Kinet S, …, Sitbon M, Taylor N
Cell 2008 Mar 21 132(6):1039-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 17 Jun 2008

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells.
Ding Y, Shen S, …, Curotto de Lafaille MA, Lafaille JJ
Nat Med 2008 Feb 14(2):162-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 31 Mar 2008

TAM receptors are pleiotropic inhibitors of the innate immune response.
Rothlin CV, Ghosh S, …, Oldstone MB, Lemke G
Cell 2007 Dec 14 131(6):1124-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Grant McFadden / Anthony DeFranco / David Alpers
Evaluated 8 Jan 2008


Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.
Park EJ, Mora JR, …, von Andrian UH, Shimaoka M
J Clin Invest 2007 Sep 117(9):2526-38 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Alpers
Evaluated 24 Oct 2007

TNF-{alpha} suppresses the expression of clock genes by interfering with E-box-mediated transcription.
Cavadini G, Petrzilka S, …, Birchler T, Fontana A
Proc Natl Acad Sci U S A 2007 Jul 31 104:12843-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 17 Aug 2007

Autophagy-dependent viral recognition by plasmacytoid dendritic cells.
Lee HK, Lund JM, …, Mizushima N, Iwasaki A
Science 2007 Mar 9 315(5817):1398-401 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jim Smiley / George Yap / Barbara Rehermann / Toshinori Nakayama / David Alpers
Evaluated 15 Jun 2007

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement.
Chieppa M, Rescigno M, Huang AY, Germain RN
J Exp Med 2006 Dec 25 203(13):2841-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Alpers
Evaluated 12 Apr 2007

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes.
Fertleman CR, Baker MD, …, Gardiner RM, Rees M
Neuron 2006 Dec 7 52(5):767-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gavril Pasternak / Gerald Zamponi / Ellen A. Lumpkin / David Alpers
Evaluated 5 Mar 2007


Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.
Wang X, Venable J, …, Yates JR, Balch WE
Cell 2006 Nov 17 127(4):803-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 25 Jan 2007

The emergence of geometric order in proliferating metazoan epithelia.
Gibson MC, Patel AB, Nagpal R, Perrimon N
Nature 2006 Aug 31 442(7106):1038-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jennifer Zallen / Laura Johnston / Thomas Lecuit / Ken Irvine / David Alpers
Evaluated 7 Nov 2006

The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion.
Roepke TK, Anantharam A, …, Lerner DJ, Abbott GW
J Biol Chem 2006 Aug 18 281(33):23740-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Alpers
Evaluated 10 Oct 2006

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.
Liu PT, Stenger S, …, Bloom BR, Modlin RL
Science 2006 Mar 24 311(5768):1770-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Luciano Adorini / Jean Pieters / Lieping Chen / Thomas Nutman / David Alpers
Evaluated 22 Jun 2006


Coding of odors by a receptor repertoire.
Hallem EA, Carlson JR
Cell 2006 Apr 7 125(1):143-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 26 Apr 2006

p120-catenin mediates inflammatory responses in the skin.
Perez-Moreno M, Davis MA, …, Reynolds AB, Fuchs E
Cell 2006 Feb 10 124(3):631-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Avri Ben-Ze'ev / David Alpers / Valeri Vasioukhin / Frans Van Roy / Kathleen J. Green
Evaluated 23 Feb 2006

Microbial regulation of intestinal radiosensitivity.
Crawford PA, Gordon JI
Proc Natl Acad Sci U S A 2005 Sep 13 102(37):13254-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Henry Lin / David Alpers
Evaluated 6 Jan 2006

The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes.
Kim DW, Lenzen G, …, Sansonetti PJ, Parsot C
Proc Natl Acad Sci U S A 2005 Sep 27 102(39):14046-51 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Craig Roy / Rino Rappuoli / David Alpers / Andrew S. Neish
Evaluated 1 Nov 2005

Gut microorganisms, mammalian metabolism and personalized health care.
Nicholson JK, Holmes E, Wilson ID
Nat Rev Microbiol 2005 May 3(5):431-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 29 Sep 2005

Inhibitory influence of chromogranin A N-terminal fragment (vasostatin-1) on the spontaneous contractions of rat proximal colon.
Amato A, Corti A, Serio R, Mulè F
Regul Pept 2005 Aug 15 130(1-2):42-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 21 Jul 2005

Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene.
Tanner SM, Li Z, …, Gräsbeck R, de la Chapelle A
Proc Natl Acad Sci U S A 2005 Mar 15 102(11):4130-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Alpers
Evaluated 8 Jun 2005

Deep brain stimulation for treatment-resistant depression.
Mayberg HS, Lozano AM, …, Schwalb JM, Kennedy SH
Neuron 2005 Mar 3 45(5):651-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Guy McKhann / David Alpers / Karen Berman
Evaluated 26 Apr 2005


Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells.
Meder D, Shevchenko A, Simons K, Füllekrug J
J Cell Biol 2005 Jan 17 168(2):303-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Alpers / Heike Folsch
Evaluated 16 Mar 2005

Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter.
Heinz A, Braus DF, …, Mann K, Büchel C
Nat Neurosci 2005 Jan 8(1):20-1 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Alpers
Evaluated 21 Jan 2005

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