7-Oct-2008
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Xiayang Qiu
Pfizer Inc., United States of America
Faculty Member: Structural Biology > Biomacromolecule-Ligand Interactions [ since 6 May 2004 ]
[
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Evaluations
Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method.
Dai SY, Chalmers MJ, …, Dodge JA, Griffin PR
Proc Natl Acad Sci U S A
2008 May 20
105
(20):7171-6 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Ross Weatherman / Xiayang Qiu
Evaluated 24 Jun 2008
Structural identification of the pathway of long-range communication in an allosteric enzyme.
Gandhi PS, Chen Z, Mathews FS, Di Cera E
Proc Natl Acad Sci U S A
2008 Feb 12
105
(6):1832-7 [
abstract on PubMed
] [
related articles
] [
full text
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order article
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Selected by
| Barry Stoddard / Xiayang Qiu
Evaluated 14 Apr 2008
Structural basis for gate-DNA recognition and bending by type IIA topoisomerases.
Dong KC, Berger JM
Nature
2007 Dec 20
450
(7173):1201-5 [
abstract on PubMed
] [
related articles
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full text
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order article
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Selected by
| Xiayang Qiu
Evaluated 3 Jan 2008
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Cherezov V, Rosenbaum DM, …, Kobilka BK, Stevens RC
Science
2007 Nov 23
318
(5854):1258-65 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Xiayang Qiu / Mark von Zastrow / Peter Artymiuk / Patricia C. Weber / Ram Samudrala / Petra Fromme / Marc Caron
Evaluated 31 Oct 2007
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
Rosenbaum DM, Cherezov V, …, Stevens RC, Kobilka BK
Science
2007 Nov 23
318
(5854):1266-73 [
abstract on PubMed
] [
related articles
] [
full text
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order article
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Selected by
| Xiayang Qiu / Senyon Choe / Marc Caron / Thomas Baranski
Evaluated 31 Oct 2007
An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.
Rock FL, Mao W, …, Cusack S, Alley MR
Science
2007 Jun 22
316
(5832):1759-61 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
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Selected by
| Celerino Abad-Zapatero / Xiayang Qiu / Dennis Hall / Anne-Catherine Dock-Bregeon
Evaluated 9 Jul 2007
A general amphipathic alpha-helical motif for sensing membrane curvature.
Drin G, Casella JF, …, Schwartz TU, Antonny B
Nat Struct Mol Biol
2007 Feb
14
(2):138-46 [
abstract on PubMed
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related articles
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full text
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order article
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Selected by
| Roger Williams / Xiayang Qiu / Edwin Chapman / Alfred Wittinghofer
Evaluated 20 Mar 2007
Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis.
Lovering AL, de Castro LH, Lim D, Strynadka NC
Science
2007 Mar 9
315
(5817):1402-5 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
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Selected by
| John Ladbury / Xiayang Qiu / David Popham
Evaluated 20 Mar 2007
Quantitative dynamics and binding studies of the 20S proteasome by NMR.
Sprangers R, Kay LE
Nature
2007 Feb 8
445
(7128):618-22 [
abstract on PubMed
] [
related articles
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full text
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order article
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Selected by
| Russ Hille / Xiayang Qiu / Antonio Rosato / Dorothee Kern / Gottfried Otting / Josep Rizo
Evaluated 14 Feb 2007
Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Angers S, Li T, …, Moon RT, Zheng N
Nature
2006 Oct 5
443
(7111):590-3 [
abstract on PubMed
] [
related articles
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full text
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order article
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Selected by
| Judy Callis / Xiayang Qiu
Evaluated 19 Oct 2006
Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli.
Rafi S, Novichenok P, …, Simmerling C, Tonge PJ
J Biol Chem
2006 Dec 22
281
(51):39285-93 [
abstract on PubMed
] [
related articles
] [
FREE full text
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Selected by
| Xiayang Qiu
Evaluated 18 Oct 2006
Ammonia channel couples glutaminase with transamidase reactions in GatCAB.
Nakamura A, Yao M, …, Sakai N, Tanaka I
Science
2006 Jun 30
312
(5782):1954-8 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Xiayang Qiu
Evaluated 18 Jul 2006
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Zhang X, Gureasko J, …, Cole PA, Kuriyan J
Cell
2006 Jun 16
125
(6):1137-49 [
abstract on PubMed
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related articles
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full text
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order article
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Selected by
| Giulio Superti-Furga / Stevan Hubbard / Xiayang Qiu / Gourisankar Ghosh / Karen Anderson / Elizabeth Goldsmith / Friedemann Kiefer / Jane Endicott / Frank Sicheri
Evaluated 27 Jun 2006
Platensimycin is a selective FabF inhibitor with potent antibiotic properties.
Wang J, Soisson SM, …, Cully D, Singh SB
Nature
2006-05-18
441
(7091):358-61 [
abstract on PubMed
] [
related articles
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full text
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order article
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Selected by
| Xiayang Qiu / Joern Piel / Liang Tong / Russell Hill / Jean-Jacques Sanglier / Jean Pieters
Evaluated 25 May 2006
Architecture of mammalian fatty acid synthase at 4.5 A resolution.
Maier T, Jenni S, Ban N
Science
2006 Mar 3
311
(5765):1258-62 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Chantal Abergel / Xiayang Qiu
Evaluated 23 Mar 2006
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.
Long SB, Campbell EB, Mackinnon R
Science
2005 Aug 5
309
(5736):897-903 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Senyon Choe / Xiayang Qiu
Evaluated 7 Oct 2005
Statistical and molecular dynamics studies of buried waters in globular proteins.
Park S, Saven JG
Proteins
2005 Aug 15
60
(3):450-63 [
abstract on PubMed
] [
related articles
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full text
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order article
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Selected by
| Xiayang Qiu
Evaluated 15 Jun 2005
A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.
Hegde SS, Vetting MW, …, Takiff HE, Blanchard JS
Science
2005 Jun 3
308
(5727):1480-3 [
abstract on PubMed
] [
related articles
] [
FREE full text
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Selected by
| Laurence Pearl / Torsten Schwede / Malcolm White / Xiayang Qiu / Brigitte Gicquel / Matt Redinbo / Peter Artymiuk / Mario Amzel / Karen Allen
Evaluated 15 Jun 2005
The modular architecture of protein-protein binding interfaces.
Reichmann D, Rahat O, …, Dym O, Schreiber G
Proc Natl Acad Sci U S A
2005 Jan 4
102
(1):57-62 [
abstract on PubMed
] [
related articles
] [
FREE full text
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Selected by
| Michael Roth / Xiayang Qiu / Sachdev Sidhu
Evaluated 29 Mar 2005
PDB-Ligand: a ligand database based on PDB for the automated and customized classification of ligand-binding structures.
Shin JM, Cho DH
Nucleic Acids Res
2005 Jan 1
33
(Database issue):D238-41 [
abstract on PubMed
] [
related articles
] [
FREE full text
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Selected by
| Xiayang Qiu
Evaluated 29 Mar 2005
Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics.
Canaves JM, Page R, Wilson IA, Stevens RC
J Mol Biol
2004 Dec 3
344
(4):977-91 [
abstract on PubMed
] [
related articles
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full text
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order article
]
Selected by
| Michael Sundstrom / Fred Dyda / Xiayang Qiu
Evaluated 4 Jan 2005
Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.
Khademi S, O'Connell J, …, Miercke LJ, Stroud RM
Science
2004 Sep 10
305
(5690):1587-94 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Tracy Palmer / Ruma Banerjee / Ian Booth / Xiayang Qiu / Wolf B. Frommer
Evaluated 28 Oct 2004
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Franklin MC, Carey KD, …, de Vos AM, Sliwkowski MX
Cancer Cell
2004 Apr
5
(4):317-28 [
abstract on PubMed
] [
related articles
] [
order article
]
Selected by
| Mark Lemmon / Xiayang Qiu
Evaluated 12 Jul 2004
Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase.
Mol CD, Dougan DR, …, Sang BC, Wilson KP
J Biol Chem
2004 Jul 23
279
(30):31655-63 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Xiayang Qiu / Daniel Flynn
Evaluated 25 May 2004
Communication between the active sites and dimer interface of a herpesvirus protease revealed by a transition-state inhibitor.
Marnett AB, Nomura AM, …, Ortiz de Montellano PR, Craik CS
Proc Natl Acad Sci U S A
2004 May 4
101
(18):6870-5 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Xiayang Qiu
Evaluated 25 May 2004
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