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David Grahame Hardie
Faculty of Life Sciences, University of Dundee, Dundee, United Kingdom

Faculty Member: CELL BIOLOGY > Cell growth & division [ since 24 February 2006 ]
[ Homepage ] [ Evaluations ]
Home page

http://www.dundee.ac.uk/biocentre/SLSBDIV6dgh.htm

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Evaluations

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle.
Taylor EB, An D, …, Feener EP, Goodyear LJ
J Biol Chem 2008 Apr 11 283(15):9787-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 1 May 2008

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators.
Chen S, Murphy J, …, Morrice NA, Mackintosh C
Biochem J 2008 Jan 15 409(2):449-59 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 1 May 2008

AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Gwinn DM, Shackelford DB, …, Turk BE, Shaw RJ
Mol Cell 2008 Apr 25 30(2):214-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie / Bruce Kemp
Evaluated 1 May 2008

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1.
Amodeo GA, Rudolph MJ, Tong L
Nature 2007 Sep 27 449(7161):492-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 22 Nov 2007

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans.
Greer EL, Dowlatshahi D, …, Gygi SP, Brunet A
Curr Biol 2007 Oct 9 17(19):1646-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 21 Nov 2007

Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Xiao B, Heath R, …, Carling D, Gamblin SJ
Nature 2007 Sep 27 449(7161):496-500 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means / David Grahame Hardie
Evaluated 21 Nov 2007

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Jäger S, Handschin C, St-Pierre J, Spiegelman BM
Proc Natl Acad Sci U S A 2007 Jul 17 104(29):12017-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 20 Jul 2007

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.
Townley R, Shapiro L
Science 2007 Mar 23 315(5819):1726-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 5 Apr 2007

AMP-activated protein kinase regulates PEPCK gene expression by direct phosphorylation of a novel zinc finger transcription factor.
Inoue E, Yamauchi J
Biochem Biophys Res Commun 2006 Dec 29 351(4):793-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 7 Dec 2006

Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.
Pang T, Xiong B, …, Shen JK, Li J
J Biol Chem 2007 Jan 5 282(1):495-506 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Grahame Hardie
Evaluated 29 Nov 2006

AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.
Treebak JT, Glund S, …, Zierath JR, Wojtaszewski JF
Diabetes 2006 Jul 55(7):2051-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Grahame Hardie
Dissenters | James Timmons
Evaluated 5 Jul 2006


Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.
Kramer HF, Witczak CA, …, Hirshman MF, Goodyear LJ
Diabetes 2006 Jul 55(7):2067-76 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Grahame Hardie
Evaluated 5 Jul 2006

Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling.
Narbonne P, Roy R
Development 2006 Feb 133(4):611-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Helen Chamberlin / Jane Hubbard / David Grahame Hardie
Evaluated 20 Jun 2006

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