1992 Chemistry degree at the University of Pavia (Italy)
1996 PhD at Imperial College of Science, Technology and Medicine, London (UK)
1997-1999 Postdoc at The Rockefeller University, New York (USA) supported by EMBO and HFSP
since 1999 Group Leader at EMBL, Heidelberg (Germany) in the Structural and Computational Biology Programme

http://www-db.embl-heidelberg.de:4321/emblGroups/per_951.html

Reconstitution, activities, and structure of the eukaryotic RNA exosome. Liu Q, Greimann JC, Lima CD Cell 2006 Dec 15 127(6):1223-37 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Megerditch Kiledjian / Elena Conti / Arlen Johnson Evaluated 10 Jan 2007 Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p. Aviv T, Lin Z, …, Smibert CA, Sicheri F Nat Struct Mol Biol 2006 Feb 13(2):168-76 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Elena Conti Evaluated 11 May 2006 Structural basis for nuclear import complex dissociation by RanGTP. Lee SJ, Matsuura Y, Liu SM, Stewart M Nature 2005 Jun 2 435(7042):693-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Elena Conti Evaluated 10 Jun 2005 Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Reverter D, Lima CD Nature 2005 Jun 2 435(7042):687-92 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 10 Jun 2005 Nuclear pore complex structure and dynamics revealed by cryoelectron tomography. Beck M, Förster F, …, Baumeister W, Medalia O Science 2004 Nov 19 306(5700):1387-90 [abstract on PubMed] [related articles] [FREE full text] Selected by | David Stokes / Elena Conti Evaluated 21 Dec 2004 Components of coated vesicles and nuclear pore complexes share a common molecular architecture. Devos D, Dokudovskaya S, …, Sali A, Rout MP PLoS Biol 2004 Dec 2(12):e380 [abstract on PubMed] [related articles] [FREE full text] Selected by | Susan Wente / Elena Conti / Sebastian Springer Evaluated 21 Dec 2004 Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex. Berke IC, Boehmer T, Blobel G, Schwartz TU J Cell Biol 2004 Nov 22 167(4):591-7 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Susan Wente / Elena Conti Evaluated 21 Dec 2004 The N-terminal domain of Nup159 forms a beta-propeller that functions in mRNA export by tethering the helicase Dbp5 to the nuclear pore. Weirich CS, Erzberger JP, Berger JM, Weis K Mol Cell 2004 Dec 3 16(5):749-60 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Susan Wente / Elena Conti Evaluated 21 Dec 2004 Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex. Petosa C, Schoehn G, …, Mattaj IW, Müller CW Mol Cell 2004 Dec 3 16(5):761-75 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Elena Conti Evaluated 21 Dec 2004 Structural basis for the assembly of a nuclear export complex. Matsuura Y, Stewart M Nature 2004 Dec 16 432(7019):872-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Elena Conti / Karsten Weis Evaluated 21 Dec 2004 Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors. Meinhart A, Cramer P Nature 2004 Jul 8 430(6996):223-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Benoit Coulombe / Gabriele Varani / Elena Conti Evaluated 12 Oct 2004 The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Kadlec J, Izaurralde E, Cusack S Nat Struct Mol Biol 2004 Apr 11(4):330-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Lynne Maquat / Elena Conti Evaluated 24 Mar 2004 Structure and stability of the ankyrin domain of the Drosophila Notch receptor. Zweifel ME, Leahy DJ, Hughson FM, Barrick D Protein Sci 2003 Nov 12(11):2622-32 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 16 Mar 2004 Crystal structure of Dcp1p and its functional implications in mRNA decapping. She M, Decker CJ, …, Parker R, Song H Nat Struct Mol Biol 2004 Mar 11(3):249-56 [abstract on PubMed] [related articles] [FREE full text] Selected by | Megerditch Kiledjian / Elena Conti Evaluated 16 Mar 2004 The structure of importin-beta bound to SREBP-2: nuclear import of a transcription factor. Lee SJ, Sekimoto T, …, Tsukihara T, Yoneda Y Science 2003 Nov 28 302(5650):1571-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Elena Conti Evaluated 7 Jan 2004 Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication. Rosendal KR, Wild K, Montoya G, Sinning I Proc Natl Acad Sci U S A 2003 Dec 9 100(25):14701-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti / Kathleen Hall Evaluated 7 Jan 2004 Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import. Matsuura Y, Lange A, …, Corbett AH, Stewart M EMBO J 2003 Oct 15 22(20):5358-69 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 24 Oct 2003 Architecture of initiation-competent 12-subunit RNA polymerase II. Armache KJ, Kettenberger H, Cramer P Proc Natl Acad Sci U S A 2003 Jun 10 100(12):6964-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 14 Aug 2003 Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor. Schwartz T, Blobel G Cell 2003 Mar 21 112(6):793-803 [abstract on PubMed] [related articles] [order article] Selected by | Elena Conti Evaluated 11 Jun 2003 Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta. Cingolani G, Bednenko J, Gillespie MT, Gerace L Mol Cell 2002 Dec 10(6):1345-53 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart / Caroline Hill / Elena Conti Evaluated 30 May 2003 The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1). Tickenbrock L, Cramer J, Vetter IR, Muller O J Biol Chem 2002 Aug 30 277(35):32332-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 8 Oct 2002 The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98. Hodel AE, Hodel MR, …, Xu S, Powers MA Mol Cell 2002 Aug 10(2):347-58 [abstract on PubMed] [related articles] [order article] Selected by | Elena Conti Evaluated 8 Oct 2002 Modular recognition of RNA by a human pumilio-homology domain. Wang X, McLachlan J, Zamore PD, Hall TM Cell 2002 Aug 23 110(4):501-12 [abstract on PubMed] [related articles] [order article] Selected by | Kiyoshi Nagai / Elena Conti Evaluated 8 Oct 2002 Molecular architecture and functional model of the endocytic AP2 complex. Collins BM, McCoy AJ, …, Evans PR, Owen DJ Cell 2002 May 17 109(4):523-35 [abstract on PubMed] [related articles] [order article] Selected by | David Barford / Rainer Duden / Scott Emr / Elena Conti Evaluated 16 Aug 2002 RanGAP mediates GTP hydrolysis without an arginine finger. Seewald MJ, Körner C, Wittinghofer A, Vetter IR Nature 2002 Feb 7 415(6872):662-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Janet Lindsley / Elena Conti / Arieh Warshel Evaluated 13 Feb 2002 Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. Kataoka N, Diem MD, …, Yong J, Dreyfuss G EMBO J 2001 Nov 15 20(22):6424-33 [abstract on PubMed] [related articles] [FREE full text] Selected by | Elena Conti Evaluated 17 Dec 2001 Crystal structure of Arp2/3 complex. Robinson RC, Turbedsky K, …, Choe S, Pollard TD Science 2001 Nov 23 294(5547):1679-84 [abstract on PubMed] [related articles] [FREE full text] Selected by | Marie-France Carlier / Elena Conti / Tony Crowther / Carien Niessen / David Lambright Evaluated 17 Dec 2001 The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly. Dutta S, Akey IV, …, Head JF, Akey CW Mol Cell 2001 Oct 8(4):841-53 [abstract on PubMed] [related articles] [order article] Selected by | Robert Dutnall / Elena Conti / Song Tan Evaluated 13 Dec 2001 Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Strässer K, Hurt E Nature 2001 Oct 11 413(6856):648-52 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Elena Conti / Anita Hopper Evaluated 15 Nov 2001 Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Renault L, Kuhlmann J, Henkel A, Wittinghofer A Cell 2001 Apr 20 105(2):245-55 [abstract on PubMed] [related articles] [order article] Selected by | Elena Conti Evaluated 11 Oct 2001 Crystal structure of the human nuclear cap binding complex. Mazza C, Ohno M, …, Mattaj IW, Cusack S Mol Cell 2001 Aug 8(2):383-96 [abstract on PubMed] [related articles] [order article] Selected by | Elena Conti Evaluated 11 Oct 2001

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