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Peter Jensen
Department of Pathology, University of Utah School of Medicine, Salt Lake City, United States of America

Faculty Member: IMMUNOLOGY > Antigen processing & recognition [ since 4 July 2001 ]
[ Evaluations ]
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Evaluations

An MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient mice.
Menges PR, Jenks SA, …, Knowlden ZA, Sant AJ
J Immunol 2008 Feb 1 180(3):1619-33 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 26 Jun 2008

Characteristics of Carbohydrate Antigen Binding to the Presentation Protein HLA-DR.
Cobb BA, Kasper DL
Glycobiology 2008 Jun 4 [abstract on PubMed] [related articles] [full text]
Selected by | Peter Jensen
Evaluated 13 Jun 2008

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.
De Gassart A, Camosseto V, …, Pierre P, Gatti E
Proc Natl Acad Sci U S A 2008 Mar 4 105(9):3491-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 30 May 2008

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells.
Huang S, Gilfillan S, …, Lantz O, Hansen TH
J Exp Med 2008 May 12 205(5):1201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 27 May 2008

Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides.
Lovitch SB, Esparza TJ, …, Herzog J, Unanue ER
J Immunol 2007 Jan 1 178(1):122-33 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 6 Jun 2007

Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection.
Chen M, Bouvier M
EMBO J 2007 Mar 21 26(6):1681-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Van Endert / Peter Jensen
Evaluated 6 Jun 2007

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation.
Firat E, Saveanu L, …, van Endert P, Niedermann G
J Immunol 2007 Feb 15 178(4):2241-8 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 13 Mar 2007

An antigen produced by splicing of noncontiguous peptides in the reverse order.
Warren EH, Vigneron NJ, …, Riddell SR, Van den Eynde BJ
Science 2006 Sep 8 313(5792):1444-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurence Eisenlohr / Peter Jensen / Barry Stoddard
Evaluated 25 Sep 2006

Probing the ligand-induced conformational change in HLA-DR1 by selective chemical modification and mass spectrometric mapping.
Carven GJ, Stern LJ
Biochemistry 2005 Oct 25 44(42):13625-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 6 Sep 2006

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability.
Lazarski CA, Chaves FA, Sant AJ
J Exp Med 2006 May 15 203(5):1319-28 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen / Paul Roche
Evaluated 18 Jul 2006

Invariant chain transmembrane domain trimerization: a step in MHC class II assembly.
Dixon AM, Stanley BJ, …, Dawson JP, Engelman DM
Biochemistry 2006 Apr 25 45(16):5228-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 12 Jun 2006

Peptide-binding motifs for the I-Ad MHC class II molecule: alternate pH-dependent binding behavior.
Chaves FA, Richards KA, …, Wedekind J, Sant AJ
Biochemistry 2006 May 23 45(20):6426-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 12 Jun 2006

Small molecules that enhance the catalytic efficiency of HLA-DM.
Nicholson MJ, Moradi B, …, Stein RL, Wucherpfennig KW
J Immunol 2006 Apr 1 176(7):4208-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 7 Jun 2006

Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex.
Peaper DR, Wearsch PA, Cresswell P
EMBO J 2005 Oct 19 24(20):3613-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen / Sebastian Springer
Evaluated 18 Nov 2005

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance.
Lazarski CA, Chaves FA, …, Weaver JM, Sant AJ
Immunity 2005 Jul 23(1):29-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 17 Aug 2005

A mutant cell with a novel defect in MHC class I quality control.
York IA, Grant EP, Dahl AM, Rock KL
J Immunol 2005 Jun 1 174(11):6839-46 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 15 Jun 2005

Polysaccharide processing and presentation by the MHCII pathway.
Cobb BA, Wang Q, Tzianabos AO, Kasper DL
Cell 2004 May 28 117(5):677-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen / Andrew Saxon / Elizabeth Mellins
Evaluated 24 Jun 2004

Supine orientation of a murine MHC class I molecule on the membrane bilayer.
Mitra AK, Célia H, …, Wilson IA, Teyton L
Curr Biol 2004 Apr 20 14(8):718-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 27 Apr 2004

Differential peptide dynamics is linked to major histocompatibility complex polymorphism.
Pöhlmann T, Böckmann RA, …, Ziegler A, Alexiev U
J Biol Chem 2004 Jul 2 279(27):28197-201 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 26 Apr 2004

Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.
Tolosa E, Li W, …, Melms A, Bromme D
J Clin Invest 2003 Aug 112(4):517-26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 27 Aug 2003

Feedback regulation of pathogen-specific T cell priming.
Wong P, Pamer EG
Immunity 2003 Apr 18(4):499-511 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen / Allan Zajac
Evaluated 9 May 2003

Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition.
Suri A, Walters JJ, …, Gross ML, Unanue ER
Proc Natl Acad Sci U S A 2003 Apr 29 100(9):5330-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 9 May 2003

Point mutations in or near the antigen-binding groove of HLA-DR3 implicate class II-associated invariant chain peptide affinity as a constraint on MHC class II polymorphism.
Doebele RC, Pashine A, …, Busch R, Mellins ED
J Immunol 2003 May 1 170(9):4683-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 9 May 2003

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.
Manoury B, Mazzeo D, …, Benaroch P, Watts C
Immunity 2003 Apr 18(4):489-98 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 9 May 2003

Activation of lysosomal function during dendritic cell maturation.
Trombetta ES, Ebersold M, …, Pypaert M, Mellman I
Science 2003 Feb 28 299(5611):1400-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen / Sergio Grinstein / David Branch Moody
Evaluated 12 Mar 2003

A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules.
Rötzschke O, Lau JM, …, Falk K, Strominger JL
Proc Natl Acad Sci U S A 2002 Dec 24 99(26):16946-50 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Andrea Sant / Peter Jensen
Evaluated 12 Mar 2003

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells.
Pasare C, Medzhitov R
Science 2003 Feb 14 299(5609):1033-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Fiona Powrie / Thomas Hunig / Peter Jensen / Matthias von Herrath / Paul Lyons
Evaluated 6 Mar 2003

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.
Michaëlsson J, Teixeira de Matos C, …, Kärre K, Söderström K
J Exp Med 2002 Dec 2 196(11):1403-14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Frank Momburg / Peter Jensen / Mary Carrington
Evaluated 17 Jan 2003

HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells.
Heinzel AS, Grotzke JE, …, Belisle JT, Lewinsohn DM
J Exp Med 2002 Dec 2 196(11):1473-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 17 Jan 2003

Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo.
Schuurhuis DH, Ioan-Facsinay A, …, Verbeek JS, Ossendorp F
J Immunol 2002 Mar 1 168(5):2240-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 17 Jan 2003

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.
Boes M, Cerny J, …, Chen J, Ploegh HL
Nature 2002 Aug 29 418(6901):983-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tim Elliott / Peter Jensen
Evaluated 13 Sep 2002

In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens.
Jung S, Unutmaz D, …, Littman DR, Lang RA
Immunity 2002 Aug 17(2):211-20 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen / John Cambier
Evaluated 13 Sep 2002

Alternate interactions define the binding of peptides to the MHC molecule IA(b).
Liu X, Dai S, …, Marrack P, Kappler J
Proc Natl Acad Sci U S A 2002 Jun 25 99(13):8820-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 4 Sep 2002

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au.
He XL, Radu C, …, Ward ES, Garcia KC
Immunity 2002 Jul 17(1):83-94 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 21 Aug 2002

Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis.
Stratikos E, Mosyak L, Zaller DM, Wiley DC
J Exp Med 2002 Jul 15 196(2):173-83 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 24 Jul 2002

Kinetics of registry selection of chimeric peptides binding to MHC II.
Belmares MP, McConnell HM
Biochemistry 2001 Aug 28 40(34):10284-92 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 8 Apr 2002

Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin.
Gao B, Adhikari R, …, Michalak M, Elliott T
Immunity 2002 Jan 16(1):99-109 [abstract on PubMed] [related articles] [order article]
Selected by | Frank Momburg / Peter Jensen
Evaluated 14 Mar 2002

Disulfide bond isomerization and the assembly of MHC class I-peptide complexes.
Dick TP, Bangia N, Peaper DR, Cresswell P
Immunity 2002 Jan 16(1):87-98 [abstract on PubMed] [related articles] [order article]
Selected by | Frank Momburg / Tim Elliott / Peter Jensen
Evaluated 13 Mar 2002

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells.
Kleijmeer M, Ramm G, …, Stoorvogel W, Geuze HJ
J Cell Biol 2001 Oct 1 155(1):53-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul Gleeson / Lisa Denzin / Judith Klumperman / Peter Jensen
Evaluated 13 Mar 2002

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.
Blanco P, Palucka AK, …, Pascual V, Banchereau J
Science 2001 Nov 16 294(5546):1540-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Andy Chan / Peter Jensen / David Branch Moody
Evaluated 11 Jan 2002

Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response.
Ohteki T, Suzue K, …, Ota T, Koyasu S
Nat Immunol 2001 Dec 2(12):1138-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Jensen
Evaluated 2 Jan 2002

Defective antigen processing in GILT-free mice.
Maric M, Arunachalam B, …, Flavell RA, Cresswell P
Science 2001 Nov 9 294(5545):1361-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen / Frank Momburg / Lisa Denzin
Evaluated 23 Nov 2001

The kinetic basis of peptide exchange catalysis by HLA-DM.
Zarutskie JA, Busch R, …, Mellins ED, Stern LJ
Proc Natl Acad Sci U S A 2001 Oct 23 98(22):12450-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 14 Nov 2001

Stability of surface H-2K(b), H-2D(b), and peptide-receptive H-2K(b) on splenocytes.
Su RC, Miller RG
J Immunol 2001 Nov 1 167(9):4869-77 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 14 Nov 2001

Mutations changing the kinetics of class II MHC peptide exchange.
Wilson N, Fremont D, Marrack P, Kappler J
Immunity 2001 May 14(5):513-22 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Jensen
Evaluated 25 Sep 2001

Energetic asymmetry among hydrogen bonds in MHC class II*peptide complexes.
McFarland BJ, Katz JF, Beeson C, Sant AJ
Proc Natl Acad Sci U S A 2001 Jul 31 98(16):9231-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 18 Sep 2001

Prolonged antigen persistence within nonterminal late endocytic compartments of antigen-specific B lymphocytes.
Gondré-Lewis TA, Moquin AE, Drake JR
J Immunol 2001 Jun 1 166(11):6657-64 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jensen
Evaluated 13 Sep 2001

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