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Vincent Pecoraro
Department of Chemistry, University of Michigan, Ann Arbor, United States of America

Faculty Member: Chemical Biology > Bioinorganic Chemistry [ since 20 August 2002 ]
[ Biography ] [ Homepage ] [ Evaluations ]
Biography

Research Interests:
Synthetic models for the active site structure and chemical mechanism of manganese enzymes.
Development of the chemistry of metallacrowns.
Biological chemistry of vanadium.
De Novo metallopeptide design.
EXPERIENCE:
Professor, University of Michigan, Ann Arbor, MI 1992-Present.
Associate Faculty Member of Biophysics Program, 1991-present.
Visiting Research Fellow, Merck Research Laboratories, Rahway, New Jersey 8/6/97-1/5/98.
Visiting Professor, Princeton University, Princeton, New Jersey 9/29/97-12/31/97.
Professeur Associate, Universite de Paris-Sud, Orsay, France 4/1/98-5/15/98.
Visiting Associate Professor, University of North Carolina, Chapel Hill, 1991.
Associate Professor, University of Michigan, Ann Arbor, MI 1989-1992.
Assistant Professor, University of Michigan, Ann Arbor, MI 1984-1989.
Member of: Program in Biomolecular Recognition, Univ. of Michigan, 1994-present.
Cellular Biotechnology Training Program, Univ. of Michigan, 1991-present.
Molecular Biophysics Training Program, Univ. of Michigan, 1988-present.
Chemistry/Biology Interface Training Program, Univ. of Michigan, 1996-present.
Executive Committees: Molecular Biophysics Training Program, 1988-92; Center for Molecular Genetics, 1987-90; Biophysics Research
Division, 1995-7.
Acting Principal Investigator, Molecular Biophysics Training Program, 1989-90.

Awards and Professional Activities:
NIH Postdoctoral Fellow(1981-4).
Horace H. Rackham Fellow(1985).
Lilly Teaching Fellow (1985).
G.D. Searle Biomedical Research Scholar(1986-9).
Alfred P. Sloan Fellow (1989-91).
U of M Faculty Recogniton Award (1993).
Akron Section Award: Excellence in Chemistry (1995).
Mary Kapp Lecturer, VCU (1997).
Editorial Board, ACS Books (1992-6).
Associate Editor Inorganic Chemistry (9/1/94-present).
JBIC Publications Committee 1996-2000.
Chairman, Keystone Symposia on Cellular and Molecular Biology, The Metal Ion/Molecular Biology Interface, 1992.
Chairman, Gordon Conference, Metals in Biology, Ventura, California, 2000.
Vice Chairman, International COnference on Bioinorganic Chemistry, Ann Arbor, MI
American Chemical Society (Local Section): Chairman (1990-92), Local Section Councilor (1989-92), Membership Affairs Committee
(1989-95).
American Society of Biochemists and Molecular Biologists.
NIH Study Sections: Chemistry/Biology Interface (CBI, 1993); Metallobiochemistry (BMT, 1993-6).
Alexander von Humboldt Award to Senior Scientists (1997)
Karcher Lecturer, University of Oklahoma (1999)
Plenary Lecturer, International Conference on Applied Bioinorganic Chemistry (1999)
Plenary Lecturer, International Conference on Bioinorganic Chemistry (2001)
Councilor, Society of Biological Inorganic Chemists (1999-2003)
Fellow, American Association for the Advancement of Science (2000-present)
IUPAC Young Investigator (2001).
Advisory Board, ACS Petroleum Research Fund, 2001-2004.
Advisory Subcommittee, Division of Chemical Nomenclature and Structure Representation, IUPAC, 2001-2003

Home page

http://www-personal.umich.edu/~vlpec/

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Evaluations

The possible role of proton-coupled electron transfer (PCET) in water oxidation by photosystem II.
Meyer TJ, Huynh MH, Thorp HH
Angew Chem Int Ed Engl 2007 46(28):5284-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vincent Pecoraro
Evaluated 19 Dec 2007

Where water is oxidized to dioxygen: structure of the photosynthetic Mn4Ca cluster.
Yano J, Kern J, …, Zouni A, Yachandra VK
Science 2006 Nov 3 314(5800):821-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 15 Nov 2006

Photosynthetic O2 formation tracked by time-resolved x-ray experiments.
Haumann M, Liebisch P, …, Grabolle M, Dau H
Science 2005 Nov 11 310(5750):1019-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 30 Nov 2005

Zinc-porphyrin Solvation in folded and unfolded states of Zn-cytochrome c.
Kim JE, Pribisko MA, Gray HB, Winkler JR
Inorg Chem 2004 Dec 13 43(25):7953-60 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Insights into partially folded or unfolded States of metalloproteins from nuclear magnetic resonance.
Turano P
Inorg Chem 2004 Dec 13 43(25):7945-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Folding, conformational changes, and dynamics of cytochromes C probed by NMR spectroscopy.
Bren KL, Kellogg JA, Kaur R, Wen X
Inorg Chem 2004 Dec 13 43(25):7934-44 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Role of cofactors in folding of the blue-copper protein azurin.
Wittung-Stafshede P
Inorg Chem 2004 Dec 13 43(25):7926-33 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Design, folding, and activities of metal-assembled coiled coil proteins.
Doerr AJ, McLendon GL
Inorg Chem 2004 Dec 13 43(25):7916-25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Site selection in tandem arrays of metal-binding domains.
Thickman KR, Davis A, Berg JM
Inorg Chem 2004 Dec 13 43(25):7897-901 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro
Evaluated 21 Feb 2005

Forced folding and structural analysis of metastable proteins.
Peterson RW, Anbalagan K, Tommos C, Wand AJ
J Am Chem Soc 2004 Aug 11 126(31):9498-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vincent Pecoraro / Antonio Rosato
Evaluated 9 Aug 2004

Characterization of a dinuclear MnV=O complex and is efficient evolution of O2 in the presence of water.
Shimazaki Y, Nagano T, …, Tani F, Naruta Y
Angew Chem Int Ed Engl 2004 Jan 43(1):98-100 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marc Fontecave / Vincent Pecoraro
Evaluated 16 Feb 2004

Architecture of the photosynthetic oxygen-evolving center.
Ferreira KN, Iverson TM, …, Barber J, Iwata S
Science 2004 Mar 19 303(5665):1831-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vincent Pecoraro / Wolfgang Junge
Evaluated 16 Feb 2004

Rational design of a calcium-binding protein.
Yang W, Jones LM, …, Ghazi M, Yang JJ
J Am Chem Soc 2003 May 21 125(20):6165-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vincent Pecoraro
Evaluated 10 Jun 2003

Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.
Kamiya N, Shen JR
Proc Natl Acad Sci U S A 2003 Jan 7 100(1):98-103 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Wolfgang Junge / Vincent Pecoraro
Evaluated 12 Feb 2003

Long-distance magnetic interaction between a Mn(III)Mn(IV) (S=1/2) core and an organic radical: a spectroscopic model for the S(2)Y(Z). state of photosystem II.
Marlin DS, Bill E, …, Rentschler E, Wieghardt K
Angew Chem Int Ed Engl 2002 Dec 16 41(24):4775-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vincent Pecoraro
Evaluated 12 Feb 2003

Acetate binding at the photosystem II oxygen evolving complex: an S(2)-state multiline signal ESEEM study.
Clemens KL, Force DA, Britt RD
J Am Chem Soc 2002 Sep 11 124(36):10921-33 [abstract on PubMed] [related articles] [order article]
Selected by | Vincent Pecoraro
Evaluated 10 Oct 2002

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