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Laurence Eisenlohr
Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, United States of America

Faculty Member: IMMUNOLOGY > Antigen processing & recognition [ since 28 February 2006 ]
[ Evaluations ]
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Evaluations

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation.
Burgdorf S, Schölz C, …, Tampé R, Kurts C
Nat Immunol 2008 May 9(5):558-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ted Hansen / Laurence Eisenlohr
Evaluated 2 May 2008

A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.
Stemberger C, Huster KM, …, Wagner H, Busch DH
Immunity 2007 Dec 27(6):985-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Allan Zajac / Etienne Joly / Laurence Eisenlohr
Evaluated 18 Feb 2008

CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity.
Bijker MS, van den Eeden SJ, …, Offringa R, van der Burg SH
J Immunol 2007 Oct 15 179(8):5033-40 [abstract on PubMed] [related articles] [order article]
Selected by | Laurence Eisenlohr
Evaluated 28 Nov 2007

Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection.
Munks MW, Pinto AK, Doom CM, Hill AB
J Immunol 2007 Jun 1 178(11):7235-41 [abstract on PubMed] [related articles] [order article]
Selected by | Laurence Eisenlohr
Evaluated 9 Oct 2007

Killer T cells regulate antigen presentation for early expansion of memory, but not naive, CD8+ T cell.
Belz GT, Zhang L, …, Kupresanin F, Davenport MP
Proc Natl Acad Sci U S A 2007 Apr 10 104(15):6341-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurence Eisenlohr
Evaluated 28 Aug 2007

Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer.
Wearsch PA, Cresswell P
Nat Immunol 2007 Aug 8(8):873-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Van Endert / Laurence Eisenlohr
Evaluated 13 Aug 2007

Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin.
Kienast A, Preuss M, Winkler M, Dick TP
Nat Immunol 2007 Aug 8(8):864-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Van Endert / Laurence Eisenlohr
Evaluated 13 Aug 2007

Regulation of CD8+ T cell development by thymus-specific proteasomes.
Murata S, Sasaki K, …, Takahama Y, Tanaka K
Science 2007 Jun 1 316(5829):1349-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kristin Hogquist / Brigitte Huber / Torben Lund / Laurence Eisenlohr / Edward Collins / Peter Van Endert
Evaluated 19 Jun 2007

Reconstruction of a pathway of antigen processing and class II MHC peptide capture.
Moss CX, Tree TI, Watts C
EMBO J 2007 Apr 18 26(8):2137-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurence Eisenlohr / Elizabeth Mellins
Evaluated 4 Apr 2007

A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells.
Ackerman AL, Giodini A, Cresswell P
Immunity 2006 Oct 25(4):607-17 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Edward Collins / Laurence Eisenlohr / Frank Momburg
Evaluated 23 Nov 2006

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.
Park B, Lee S, …, Cho S, Ahn K
Cell 2006 Oct 20 127(2):369-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Mayinger / Karin Romisch / Laurence Eisenlohr / Jean Pieters / Elizabeth Mellins
Evaluated 14 Nov 2006

Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination.
Shin JS, Ebersold M, …, Hartley A, Mellman I
Nature 2006 Nov 2 444(7115):115-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurence Eisenlohr / Torben Lund / Heike Folsch / Clifford Harding / Elizabeth Mellins
Evaluated 30 Oct 2006

An antigen produced by splicing of noncontiguous peptides in the reverse order.
Warren EH, Vigneron NJ, …, Riddell SR, Van den Eynde BJ
Science 2006 Sep 8 313(5792):1444-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurence Eisenlohr / Peter Jensen / Barry Stoddard
Evaluated 21 Sep 2006

Herpes simplex virus evades natural killer T cell recognition by suppressing CD1d recycling.
Yuan W, Dasgupta A, Cresswell P
Nat Immunol 2006 Aug 7(8):835-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter van der Sluijs / Laurence Eisenlohr / Lutz Walter
Evaluated 18 Aug 2006


The double lysine motif of tapasin is a retrieval signal for retention of unstable MHC class I molecules in the endoplasmic reticulum.
Paulsson KM, Jevon M, …, Li S, Wang P
J Immunol 2006 Jun 15 176(12):7482-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurence Eisenlohr
Evaluated 18 Jul 2006

Hsp90alpha chaperones large C-terminally extended proteolytic intermediates in the MHC class I antigen processing pathway.
Kunisawa J, Shastri N
Immunity 2006 May 24(5):523-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ted Hansen / Laurence Eisenlohr / Peter Van Endert
Evaluated 12 Jun 2006

Toll-dependent selection of microbial antigens for presentation by dendritic cells.
Blander JM, Medzhitov R
Nature 2006 Apr 6 440(7085):808-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Karp / Torben Lund / Peter Van Endert / Elizabeth Mellins / David Branch Moody / Dan Conrad / Laurence Eisenlohr / Etienne Joly / Marcus Thelen / Victor Nizet
Evaluated 24 Apr 2006

Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells.
Crawford A, Macleod M, …, Corlett L, Gray D
J Immunol 2006 Mar 15 176(6):3498-506 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurence Eisenlohr
Evaluated 16 Mar 2006

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