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Giulio Gabbiani
Department of Pathology, University of Geneva, Geneva, Switzerland

Faculty Member: PHYSIOLOGY > Cardiovascular physiology/circulation [ since 4 July 2005 ]
[ Evaluations ]
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Evaluations

Sphingosine-1-Phosphate Receptor Subtypes Differentially Regulate Smooth Muscle Cell Phenotype.
Wamhoff BR, Lynch KR, Macdonald TL, Owens GK
Arterioscler Thromb Vasc Biol 2008 Jun 5 [abstract on PubMed] [related articles] [full text]
Selected by | Giulio Gabbiani
Evaluated 27 Jun 2008

Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells.
Mishra PJ, Mishra PJ, …, Glod JW, Banerjee D
Cancer Res 2008 Jun 1 68(11):4331-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 20 Jun 2008

Fibroblast adhesion results in the induction of a matrix remodeling gene expression program.
Kennedy L, Shi-Wen X, …, Abraham DJ, Leask A
Matrix Biol 2008 May 27(4):274-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 18 Jun 2008

Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes.
Hawsawi NM, Ghebeh H, …, Dermime S, Aboussekhra A
Cancer Res 2008 Apr 15 68(8):2717-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 12 May 2008

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling.
Huet E, Vallée B, …, Menashi S, Gabison EE
FASEB J 2008 Apr 22(4):1144-54 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 9 May 2008

Coexpression of myofibroblast and macrophage markers: novel evidence for an in vivo plasticity of chorioamniotic mesodermal cells of the human placenta.
Kim SS, Romero R, …, Yoon BH, Kim CJ
Lab Invest 2008 Apr 88(4):365-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 2 May 2008

Tensile forces govern germ-layer organization in zebrafish.
Krieg M, Arboleda-Estudillo Y, …, Müller DJ, Heisenberg CP
Nat Cell Biol 2008 Apr 10(4):429-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani / Erez Raz / Christopher Chen
Evaluated 10 Apr 2008

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events.
Mullick AE, Soldau K, …, Tobias PS, Curtiss LK
J Exp Med 2008 Feb 4 [abstract on PubMed] [related articles] [full text]
Selected by | Giulio Gabbiani
Evaluated 19 Feb 2008

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring.
Mori R, Shaw TJ, Martin P
J Exp Med 2008 Jan 21 205(1):43-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 24 Jan 2008

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix.
Wipff PJ, Rifkin DB, Meister JJ, Hinz B
J Cell Biol 2007 Dec 17 179:1311-23 [abstract on PubMed] [related articles] [order article]
Selected by | Giulio Gabbiani / Carol Otey
Evaluated 3 Jan 2008


Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis.
Liu T, Warburton RR, …, Gaestel M, Kayyali US
Am J Respir Cell Mol Biol 2007 Nov 37(5):507-17 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 11 Dec 2007

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
Nahrendorf M, Swirski FK, …, Weissleder R, Pittet MJ
J Exp Med 2007 Nov 26 204(12):3037-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani / Noel Rose
Evaluated 28 Nov 2007

Ena/VASP is required for endothelial barrier function in vivo.
Furman C, Sieminski AL, …, Fässler R, Gertler FB
J Cell Biol 2007 Nov 19 179(4):761-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani / Valeri Vasioukhin
Evaluated 19 Nov 2007

Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment.
Mueller L, Goumas FA, …, Rogiers X, Broering DC
Am J Pathol 2007 Nov 171(5):1608-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 6 Nov 2007

Thy-1 is expressed in hepatic myofibroblasts and not oval cells in stem cell-mediated liver regeneration.
Dezso K, Jelnes P, …, Bisgaard HC, Nagy P
Am J Pathol 2007 Nov 171(5):1529-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 15 Oct 2007


Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression.
Gan Q, Yoshida T, Li J, Owens GK
Circ Res 2007 Oct 26 101(9):883-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 25 Sep 2007

Myofibroblasts induce ectopic activity in cardiac tissue.
Miragoli M, Salvarani N, Rohr S
Circ Res 2007 Oct 12 101(8):755-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 24 Sep 2007

Induction of myofibroblastic differentiation in vitro by covalently immobilized transforming growth factor-beta(1).
Metzger W, Grenner N, …, Pohlemann T, Oberringer M
Tissue Eng 2007 Nov 13(11):2751-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 17 Sep 2007

Functionally specialized junctions between endothelial cells of lymphatic vessels.
Baluk P, Fuxe J, …, Dejana E, McDonald DM
J Exp Med 2007 Oct 1 204(10):2349-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani / William A Muller
Evaluated 17 Sep 2007

Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair.
Fujita J, Mori M, …, Ando K, Fukuda K
Stem Cells 2007 Nov 25(11):2750-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 17 Aug 2007

Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1.
Sakata D, Taniguchi H, …, Minato N, Narumiya S
J Exp Med 2007 Sep 3 204(9):2031-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 15 Aug 2007

TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healing.
Goldberg MT, Han YP, …, Shaw MC, Garner WL
J Invest Dermatol 2007 Nov 127(11):2645-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 12 Jul 2007

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.
Gadea G, de Toledo M, Anguille C, Roux P
J Cell Biol 2007 Jul 2 178(1):23-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 6 Jul 2007

Evidence of intercellular coupling between co-cultured adult rabbit ventricular myocytes and myofibroblasts.
Chilton L, Giles WR, Smith GL
J Physiol 2007 Aug 15 583(Pt 1):225-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 4 Jul 2007

Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2.
Sousa AM, Liu T, …, Toksoz D, Kayyali US
J Cell Biochem 2007 Apr 15 100(6):1581-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 16 May 2007

Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis.
Fuster MM, Wang L, …, Sriramarao P, Esko JD
J Cell Biol 2007 May 7 177(3):539-49 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 15 May 2007

Alpha-smooth muscle actin expression enhances cell traction force.
Chen J, Li H, SundarRaj N, Wang JH
Cell Motil Cytoskeleton 2007 Apr 64(4):248-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 25 Apr 2007

Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1.
Jain R, Shaul PW, Borok Z, Willis BC
Am J Respir Cell Mol Biol 2007 Jul 37(1):38-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 3 Apr 2007

Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease.
Sadlonova A, Mukherjee S, …, Novak L, Frost AR
Am J Pathol 2007 Mar 170(3):1064-76 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 27 Mar 2007

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.
Orr AW, Stockton R, …, Blackman BR, Schwartz MA
J Cell Biol 2007 Feb 26 176(5):719-27 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 1 Mar 2007

Clonal characterization of fibroblasts in the superficial layer of the adult human dermis.
Sorrell JM, Baber MA, Caplan AI
Cell Tissue Res 2007 Mar 327(3):499-510 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 15 Feb 2007

Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway.
Fan L, Sebe A, …, Mucsi I, Kapus A
Mol Biol Cell 2007 Mar 18(3):1083-97 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 29 Jan 2007

Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation.
Clément S, Stouffs M, …, Chaponnier C, Jaconi M
J Cell Sci 2007 Jan 15 120(Pt 2):229-38 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 19 Jan 2007

Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype.
Clempus RE, Sorescu D, …, Lassègue B, Griendling KK
Arterioscler Thromb Vasc Biol 2007 Jan 27(1):42-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 19 Jan 2007

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility.
Sahai E, Garcia-Medina R, Pouysségur J, Vial E
J Cell Biol 2007 Jan 1 176(1):35-42 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani / Christopher Marshall
Evaluated 9 Jan 2007

Force sensing by mechanical extension of the Src family kinase substrate p130Cas.
Sawada Y, Tamada M, …, Tanaka S, Sheetz MP
Cell 2006 Dec 1 127(5):1015-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Deborah Leckband / Giulio Gabbiani / Kenneth Yamada / Christopher Turner / Toshihiko Ogura
Evaluated 3 Jan 2007

Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice.
Bentzon JF, Weile C, …, Kassem M, Falk E
Arterioscler Thromb Vasc Biol 2006 Dec 26(12):2696-702 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 18 Dec 2006

IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.
Weng H, Mertens PR, Gressner AM, Dooley S
J Hepatol 2007 Feb 46(2):295-303 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 18 Dec 2006

Inhibition of Rho A activity causes pemphigus skin blistering.
Waschke J, Spindler V, …, Schmidt G, Drenckhahn D
J Cell Biol 2006 Dec 4 175(5):721-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 18 Dec 2006


Phenotypic conversion leads to structural and functional changes of smooth muscle sarcolemma.
Matschke K, Babiychuk EB, Monastyrskaya K, Draeger A
Exp Cell Res 2006 Nov 1 312(18):3495-503 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 1 Dec 2006

Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
Meyer-ter-Vehn T, Sieprath S, …, Grehn F, Schlunck G
Invest Ophthalmol Vis Sci 2006 Nov 47(11):4895-904 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 27 Nov 2006

Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis.
Gazdhar A, Fachinger P, …, Schmid RA, Geiser T
Am J Physiol Lung Cell Mol Physiol 2007 Feb 292(2):L529-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 13 Nov 2006

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.
Clarke MC, Figg N, …, Littlewood TD, Bennett MR
Nat Med 2006 Sep 12(9):1075-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani / Stephen Schwartz
Evaluated 13 Sep 2006

TGF-beta1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing alpha-smooth muscle actin expression.
Chen CA, Hwang JC, …, Tsai JC, Chen HC
Transl Res 2006 Sep 148(3):134-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 11 Sep 2006

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix.
Kim KK, Kugler MC, …, Sheppard D, Chapman HA
Proc Natl Acad Sci U S A 2006 Aug 29 103(35):13180-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani / Mina J. Bissell
Evaluated 6 Sep 2006

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.
Zhao M, Song B, …, McCaig CD, Penninger JM
Nature 2006 Jul 27 442(7101):457-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kenneth Yamada / Giulio Gabbiani
Evaluated 18 Aug 2006

Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation.
Chaqour B, Yang R, Sha Q
J Biol Chem 2006 Jul 21 281(29):20608-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 20 Jul 2006

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation.
Rönty MJ, Leivonen SK, …, Kähäri VM, Carpén OM
J Invest Dermatol 2006 Nov 126(11):2387-96 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 11 Jul 2006

Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils.
Wang S, Voisin MB, …, Sorokin L, Nourshargh S
J Exp Med 2006 Jun 12 203(6):1519-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William A Muller / Dietmar Vestweber / Giulio Gabbiani / David Bates / Giorgio Berton
Evaluated 26 Jun 2006

Species-specific fibroblasts required for triggering invasiveness of partially transformed oral keratinocytes.
Costea DE, Kulasekara K, …, Johannessen AC, Vintermyr OK
Am J Pathol 2006 Jun 168(6):1889-97 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 8 Jun 2006

Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1.
Davie NJ, Gerasimovskaya EV, …, Reeves JT, Stenmark KR
Am J Pathol 2006 Jun 168(6):1793-807 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 2 Jun 2006

Stress fibers are generated by two distinct actin assembly mechanisms in motile cells.
Hotulainen P, Lappalainen P
J Cell Biol 2006 May 8 173(3):383-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani / Matthew Welch / Kenneth Yamada / Marie-France Carlier / Helen Gruber
Evaluated 12 May 2006

Galectin-3 regulates myofibroblast activation and hepatic fibrosis.
Henderson NC, Mackinnon AC, …, Simpson KJ, Sethi T
Proc Natl Acad Sci U S A 2006 Mar 28 103(13):5060-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 20 Apr 2006

Essential role of Smad3 in angiotensin II-induced vascular fibrosis.
Wang W, Huang XR, …, Bottinger EP, Lan HY
Circ Res 2006 Apr 28 98(8):1032-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 31 Mar 2006

A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healing.
Bandyopadhyay B, Fan J, …, Woodley DT, Li W
J Cell Biol 2006 Mar 27 172(7):1093-105 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 23 Mar 2006

Identification of differential protein expression associated with development of unstable human carotid plaques.
Slevin M, Elasbali AB, …, Badimon L, Gaffney J
Am J Pathol 2006 Mar 168(3):1004-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 20 Mar 2006

Bone marrow lacks a transplantable progenitor for smooth muscle type alpha-actin-expressing cells.
Yokota T, Kawakami Y, …, Kincade PW, Sato S
Stem Cells 2006 Jan 24(1):13-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 2 Mar 2006

Electrotonic modulation of cardiac impulse conduction by myofibroblasts.
Miragoli M, Gaudesius G, Rohr S
Circ Res 2006 Mar 31 98(6):801-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 2 Mar 2006

Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts.
Asano Y, Ihn H, …, Jinnin M, Tamaki K
Am J Pathol 2006 Feb 168(2):499-510 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 28 Feb 2006

Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap.
Adams LD, Geary RL, …, Rossini A, Schwartz SM
Arterioscler Thromb Vasc Biol 2006 Feb 26(2):319-25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 17 Feb 2006

Isolation of "side population" progenitor cells from healthy arteries of adult mice.
Sainz J, Al Haj Zen A, …, Lemitre M, Lafont A
Arterioscler Thromb Vasc Biol 2006 Feb 26(2):281-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 17 Feb 2006

Autophagic cardiomyocyte death in cardiomyopathic hamsters and its prevention by granulocyte colony-stimulating factor.
Miyata S, Takemura G, …, Fujiwara T, Fujiwara H
Am J Pathol 2006 Feb 168(2):386-97 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 31 Jan 2006

Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage.
Frid MG, Brunetti JA, …, van Rooijen N, Stenmark KR
Am J Pathol 2006 Feb 168(2):659-69 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani / Jason Yuan
Evaluated 31 Jan 2006

Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers.
Goffin JM, Pittet P, …, Meister JJ, Hinz B
J Cell Biol 2006 Jan 16 172(2):259-68 [abstract on PubMed] [