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 | John Helmann
Department of Microbiology, Cornell University, United States of America | | | Faculty Member: CHEMICAL BIOLOGY > Bioinorganic chemistry [ since 6 August 2003 ] |
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John Helmann earned bachelor's degrees in Chemistry and Biology (University of California, Santa Cruz) in 1982. He then joined the Department of Biochemistry at the University of California at Berkeley where he studied bacterial RNA polymerase with Dr. Michael Chamberlin and earned a Ph.D. in 1987. From 1987 to 1990, Dr. Helmann worked as a post-doctoral fellow with Dr. Christopher T. Walsh at the Harvard Medical School. His post-doctoral research, on the regulation of bacterial mercuric ion resistance determinants, was supported by the Jane Coffin Childs Memorial Medical Research Foundation. Dr. Helmann joined the Section of Microbiology at Cornell as an Assistant Professor in 1990 and joined the graduate field of Biochemistry, Molecular, and Cell Biology in 1991. He was promoted to Associate Professor in 1996 and Professor in 2002. He serves as Editor for Molecular Microbiology and Archives of Microbiology and a member of the Editorial Board for the Journal of Bacteriology.
The Helmann laboratory addresses three main areas of interest related to transcriptional control mechanisms in the model Gram positive bacterium, Bacillus subtilis. One project addresses global responses to cell envelope stress and the roles of extracytoplasmic function (ECF) sigma factors in gene regulation. A second investigates mechanisms of metal ion homeostasis and the roles of the metalloregulatory proteins Fur, Zur, and MntR. A third project is focused in two transcription factors, PerR and OhrR, that sense reactive oxygen species and coordinate oxidative stress responses.
| Home page
http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm |
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