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Joan Ruderman
Department of Cell Biology, Harvard Medical School, Boston, United States of America

Faculty Member: CELL BIOLOGY > Cell growth & division [ since 24 August 2001 ]
[ Homepage ] [ Evaluations ]
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http://cellbio.med.harvard.edu/faculty/ruderman/index.html

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Evaluations

The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells.
Suzawa M, Ingraham HA
PLoS ONE 2008 3(5):e2117 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 30 May 2008

Pollutants increase song complexity and the volume of the brain area HVC in a songbird.
Markman S, Leitner S, …, Pascoe D, Buchanan KL
PLoS ONE 2008 3(2):e1674 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 7 May 2008

Erp1/Emi2 is essential for the meiosis I to meiosis II transition in Xenopus oocytes.
Ohe M, Inoue D, Kanemori Y, Sagata N
Dev Biol 2007 Mar 1 303(1):157-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 9 Feb 2007

Bisphenol A exposure in utero disrupts early oogenesis in the mouse.
Susiarjo M, Hassold TJ, Freeman E, Hunt PA
PLoS Genet 2007 Jan 12 3(1):e5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 9 Feb 2007


Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.
Vandenberg LN, Maffini MV, …, Rubin BS, Soto AM
Endocrinology 2007 Jan 148(1):116-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 2 Jan 2007

Aurora-A kinase and inhibitor-2 regulate the cyclin threshold for mitotic entry in Xenopus early embryonic cell cycles.
Satinover DL, Brautigan DL, Stukenberg PT
Cell Cycle 2006 Oct 5(19):2268-74 [abstract on PubMed] [related articles] [order article]
Selected by | Joan Ruderman
Evaluated 2 Nov 2006

Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A.
Rubin BS, Lenkowski JR, …, Ronsheim PM, Soto AM
Endocrinology 2006 Aug 147(8):3681-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 14 Aug 2006

Direct patterning of centrosome arrays as templates for the assembly of microtubules.
Shang W, Dordick JS, Palazzo RE, Siegel RW
Biotechnol Bioeng 2006 Aug 5 94(5):1012-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 16 May 2006

The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance.
Alonso-Magdalena P, Morimoto S, …, Fuentes E, Nadal A
Environ Health Perspect 2006 Jan 114(1):106-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 2 May 2006

Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome.
Dolinoy DC, Weidman JR, Waterland RA, Jirtle RL
Environ Health Perspect 2006 Apr 114(4):567-72 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 28 Apr 2006

Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defense systems mediated by multidrug transporters.
Luckenbach T, Epel D
Environ Health Perspect 2005 Jan 113(1):17-24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 26 Sep 2005

Epigenetic transgenerational actions of endocrine disruptors and male fertility.
Anway MD, Cupp AS, Uzumcu M, Skinner MK
Science 2005 Jun 3 308(5727):1466-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman / Achim Peters / Miles Wilkinson
Evaluated 10 Jun 2005

Xenoestrogen-induced ERK-1 and ERK-2 activation via multiple membrane-initiated signaling pathways.
Bulayeva NN, Watson CS
Environ Health Perspect 2004 Nov 112(15):1481-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 24 Nov 2004

Mos mediates the mitotic activation of p42 MAPK in Xenopus egg extracts.
Yue J, Ferrell JE
Curr Biol 2004 Sep 7 14(17):1581-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 20 Sep 2004

Oocyte maturation in Xenopus laevis is blocked by the hormonal herbicide, 2,4-dichlorophenoxy acetic acid.
Stebbins-Boaz B, Fortner K, …, Sinclair K, Winger E
Mol Reprod Dev 2004 Feb 67(2):233-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 23 Feb 2004

PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.
Margolis SS, Walsh S, …, Shenolikar S, Kornbluth S
EMBO J 2003 Nov 3 22(21):5734-45 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael B. Yaffe / Deborah Morrison / Joan Ruderman
Evaluated 9 Dec 2003

Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.
Chung E, Chen RH
Nat Cell Biol 2003 Aug 5(8):748-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 8 Sep 2003

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.
Ewart-Toland A, Briassouli P, …, Linardopoulos S, Balmain A
Nat Genet 2003 Aug 34(4):403-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 4 Sep 2003

Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action.
Castoria G, Lombardi M, …, Migliaccio A, Auricchio F
J Cell Biol 2003 May 12 161(3):547-56 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 4 Sep 2003

Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle.
Stenoien DL, Sen S, Mancini MA, Brinkley BR
Cell Motil Cytoskeleton 2003 Jun 55(2):134-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 27 May 2003

Crystal structure of aurora-2, an oncogenic serine/threonine kinase.
Cheetham GM, Knegtel RM, …, Lippke JA, Austen DA
J Biol Chem 2002 Nov 8 277(45):42419-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 25 Sep 2002

Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function.
Chen SS, Chang PC, …, Tang FM, Lin YS
EMBO J 2002 Sep 2 21(17):4491-9 [abstract on PubMed] [related articles] [order article]
Selected by | Joan Ruderman
Evaluated 17 Sep 2002

Cyclin G recruits PP2A to dephosphorylate Mdm2.
Okamoto K, Li H, …, Thorgeirsson SS, Prives C
Mol Cell 2002 Apr 9(4):761-71 [abstract on PubMed] [related articles] [order article]
Selected by | Joan Ruderman
Evaluated 28 Jun 2002

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2.
Lu Z, Xu S, …, Cobb MH, Hunter T
Mol Cell 2002 May 9(5):945-56 [abstract on PubMed] [related articles] [order article]
Selected by | Joan Ruderman / Angel Nebreda / Anjana Rao
Evaluated 10 Jun 2002

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.
Berdnik D, Knoblich JA
Curr Biol 2002 Apr 16 12(8):640-7 [abstract on PubMed] [related articles] [order article]
Selected by | Joan Ruderman / William Earnshaw
Evaluated 7 Jun 2002

Emi1 is required for cytostatic factor arrest in vertebrate eggs.
Reimann JD, Jackson PK
Nature 2002 Apr 25 416(6883):850-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Timothy Yen / Joan Ruderman / Angel Nebreda
Evaluated 7 Jun 2002

Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A.
Schmitt A, Nebreda AR
Proc Natl Acad Sci U S A 2002 Apr 2 99(7):4361-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman
Evaluated 15 Apr 2002

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells.
Meraldi P, Honda R, Nigg EA
EMBO J 2002 Feb 15 21(4):483-92 [abstract on PubMed] [related articles] [order article]
Selected by | Jonathon Pines / Joan Ruderman / Sergio Moreno / David Glover / David Morgan / William Earnshaw
Evaluated 18 Feb 2002

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication.
Nash P, Tang X, …, Pawson T, Tyers M
Nature 2001 Nov 29 414(6863):514-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sara Courtneidge / Steven Reed / Jeffrey Wade Harper / John Stults / Angel Nebreda / Michael B. Yaffe / Andrius Kazlauskas / Joan Ruderman
Evaluated 18 Feb 2002

Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts.
Matsumoto Y, Maller JL
Science 2002 Jan 18 295(5554):499-502 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman / Anthony Means
Evaluated 5 Feb 2002

A peptide carrier for the delivery of biologically active proteins into mammalian cells.
Morris MC, Depollier J, …, Heitz F, Divita G
Nat Biotechnol 2001 Dec 19(12):1173-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew Belmont / Joan Ruderman
Evaluated 5 Feb 2002

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2.
Sudakin V, Chan GK, Yen TJ
J Cell Biol 2001 Sep 3 154(5):925-36 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Erich Nigg / Joan Ruderman
Evaluated 7 Nov 2001

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