Associate Professor
700 Albany Street, W507
Boston, MA 02114


The major research initiatives in Dr. Freedman¿s laboratory emphasize the regulation of pathways contributing to atherothrombotic disease and how these factors contribute to acute coronary syndromes. Her research has involved both basic pathways regulating vascular function as well as pharmacological studies of therapeutics for vascular disease. The research has been studied in the context of the cardiovascular patient population including genetic, biomarker, and pharmacological intervention studies.

Effect of the italian smoking ban on population rates of acute coronary events. Cesaroni G, Forastiere F, …, Zuccaro P, Perucci CA Circulation 2008 Mar 4 117(9):1183-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Jane Freedman Evaluated 6 Mar 2008 Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation. Anderson JL, Horne BD, …, Carlquist JF, Couma-Gen Investigators Circulation 2007 Nov 27 116(22):2563-70 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Julia Kirchheiner / Jane Freedman / Munir Pirmohamed Evaluated 17 Dec 2007 Influence of inpatient service specialty on care processes and outcomes for patients with non ST-segment elevation acute coronary syndromes. Roe MT, Chen AY, …, Ohman EM, Peterson ED Circulation 2007 Sep 4 116(10):1153-61 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Jane Freedman Evaluated 23 Oct 2007 Prognostic value of troponins in acute pulmonary embolism: a meta-analysis. Becattini C, Vedovati MC, Agnelli G Circulation 2007 Jul 24 116(4):427-33 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Jane Freedman Evaluated 7 Aug 2007 Outcomes and optimal antithrombotic therapy in women undergoing fibrinolysis for ST-elevation myocardial infarction. Mega JL, Morrow DA, …, Antman EM, Braunwald E Circulation 2007 Jun 5 115(22):2822-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Jane Freedman Evaluated 6 Jul 2007 Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease. Raghavachari N, Xu X, …, Morris SM, Gladwin MT Circulation 2007 Mar 27 115(12):1551-62 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Jane Freedman Evaluated 18 Apr 2007 Dopamine agonists and the risk of cardiac-valve regurgitation. Schade R, Andersohn F, …, Haverkamp W, Garbe E N Engl J Med 2007 Jan 4 356(1):29-38 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 25 Jan 2007 Coronary intervention for persistent occlusion after myocardial infarction. Hochman JS, Lamas GA, …, Knatterud GL, Occluded Artery Trial Investigators N Engl J Med 2006 Dec 7 355(23):2395-407 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 4 Jan 2007 First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Dyke CK, Steinhubl SR, …, Becker RC, Rusconi CP Circulation 2006 Dec 5 114(23):2490-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Günter Mayer / Jane Freedman Evaluated 4 Jan 2007 Validation of a rule for termination of resuscitation in out-of-hospital cardiac arrest. Morrison LJ, Visentin LM, …, Verbeek PR, TOR Investigators N Engl J Med 355(5):478-87 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 3 Nov 2006 Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention. Montalescot G, White HD, …, Steinhubl SR, STEEPLE Investigators N Engl J Med 2006 Sep 7 355(10):1006-17 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 20 Oct 2006 Trends in prevalence and outcome of heart failure with preserved ejection fraction. Owan TE, Hodge DO, …, Roger VL, Redfield MM N Engl J Med 2006 Jul 20 355(3):251-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 1 Sep 2006 High-dose atorvastatin after stroke or transient ischemic attack. Amarenco P, Bogousslavsky J, …, Zivin JA, Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators N Engl J Med 2006 Aug 10 355(6):549-59 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 30 Aug 2006 Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Frelinger AL, Furman MI, …, Barnard MR, Michelson AD Circulation 2006 Jun 27 113(25):2888-96 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 28 Jul 2006 Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Miyasaka Y, Barnes ME, …, Seward JB, Tsang TS Circulation 2006 Jul 11 114(2):119-25 [abstract on PubMed] [related articles] [FREE full text] Selected by | Jane Freedman Evaluated 27 Jul 2006

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